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Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Hsu-Wen Tseng Denis Clay Beulah Jose Bianca Nowlan Allison R.Pettit Marjorie Salga Fra?ois Genêt Sébastien Banzet Jean-Pierre Lévesque Dorothée Girard Kylie A.Alexander Susan M.Millard Frédéric Torossian Adrienne Anginot Whitney Fleming Jules Gueguen Marie-Emmanuelle Goriot

骨研究(英文版)2022,Vol.10Issue(2):310-325,16.
骨研究(英文版)2022,Vol.10Issue(2):310-325,16.

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Hsu-Wen Tseng 1Denis Clay 2Beulah Jose 1Bianca Nowlan 1Allison R.Pettit 1Marjorie Salga 3Fra?ois Genêt 4Sébastien Banzet 3Jean-Pierre Lévesque 4Dorothée Girard 5Kylie A.Alexander 1Susan M.Millard 5Frédéric Torossian 1Adrienne Anginot 1Whitney Fleming 6Jules Gueguen 6Marie-Emmanuelle Goriot1

作者信息

  • 1. Mater Research Institute—The University of Queensland,Woolloongabba,QLD,Australia
  • 2. INSERM UMS-44,Université de Paris-Saclay,H?pital Paul Brousse,Villejuif,France
  • 3. UPOH(Unité Péri Opératoire du Handicap,Perioperative Disability Unit),Physical and Rehabilitation Medicine department,Raymond-Poincaré Hospital,Assistance Publique-H?pitaux de Paris(AP-HP),Garches,France
  • 4. Université de Versailles Saint Quentin en Yvelines,UFR Simone Veil-Santé,END:ICAP INSERM U1179,Montigny le Bretonneux,France
  • 5. Institut de Recherche Biomédicale des Armées(IRBA),INSERM UMRS-MD,1197 Clamart,France
  • 6. INSERM UMRS-MD 1197,Université de Paris-Saclay,H?pital Paul Brousse,Villejuif ,France
  • 折叠

摘要

引用本文复制引用

Hsu-Wen Tseng,Denis Clay,Beulah Jose,Bianca Nowlan,Allison R.Pettit,Marjorie Salga,Fra?ois Genêt,Sébastien Banzet,Jean-Pierre Lévesque,Dorothée Girard,Kylie A.Alexander,Susan M.Millard,Frédéric Torossian,Adrienne Anginot,Whitney Fleming,Jules Gueguen,Marie-Emmanuelle Goriot..Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles[J].骨研究(英文版),2022,10(2):310-325,16.

基金项目

This work was partly supported by Project Grant 1101620 and Ideas Grant 1181053 from the National Health and Medical Research Council of Australia(NHMRC)and by award W81XWH-15-1-0606 from the Congressionally Approved Spinal Cord Injury Research Program of the US Department of Defense and by funds from the Mater Foundation.JPL is supported by Research Fellowship 1136130 from the NHMRC.This work was also partly funded by project grant 1101620 from the French Government Defense Procurement and Technology Agency(DGA-Direction Générale de l'Armement).The Translational Research Institute is partly funded by the Federal Government of Australia.The authors greatly acknowledge Sabrina Soaves,Bastien Rival and Muriel Nivet for technical assistance.The authors would like to thank the"Cochin HistIM Facility"for technical assistance of(Paris,France).They also highly acknowledge Prof.Philippe Denormandie and Dr.Laure Gatin(Service de Chirurgie Orthopédique,H?pital Raymond Poincaré,Garches,France)and Guillaume Genet for providing and coordinating access to NHO and muscle surgical residues.The authors also acknowledge the scientific and technical assistance at the Translational Research Institute:The University of Queensland biological resources TRI facility,histology facility,flow cytometry facility,microscopy facility and the preclinical imaging facility,which is supported by Therapeutic Innovation Australia(TIA).TIA is supported by the Australian Government through the National Collaborative Research Infrastructure Strategy(NCRIS)program. (NHMRC)

骨研究(英文版)

OACSCDSCI

2095-4700

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