Hepatocellular carcinoma-derived exosomal miRNA-761 regulates the tumor microenvironment by targeting the SOCS2/JAK2/STAT3 pathwayOA
Hepatocellular carcinoma-derived exosomal miRNA-761 regulates the tumor microenvironment by targeting the SOCS2/JAK2/STAT3 pathway
Xiao-hu Zhou;Hao Xu;Chang Xu;Ying-cai Yan;Lin-shi Zhang;Qiang Sun;Wei-lin Wang;Yan-jun Shi
Department of Hepatobiliary and Pancreatic Surgery,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaDepartment of Hepatobiliary and Pancreatic Surgery,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaDepartment of Hepatobiliary and Pancreatic Surgery,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaDepartment of Hepatobiliary and Pancreatic Surgery,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,ChinaKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310009,China
ExosomesJanus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathwaymicroRNA-761Suppressor of cytokine signaling 2Tumor microenvironment
ExosomesJanus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathwaymicroRNA-761Suppressor of cytokine signaling 2Tumor microenvironment
《世界急诊医学杂志(英文)》 2022 (5)
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379-385,7
This work was supported by the National Natural Science Foundation of China(82072203),and Natural Science Foundation of Zhejiang Province(LQ19H160025).
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