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CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant

Chenshuo Wu Xiaopeng Ma Omar A.Al-Hartomy S.Wageh Abdullah G.Al-Sehemi Zhiguang Luo Yaqing He Jingfeng Li Zhongjian Xie Han Zhang Zhi Chen Chaozhou Li Yabin Hao Yuxuan Tang Yuxuan Yuan Luxiao Chai Taojian Fan Jiangtian Yu

纳微快报（英文）2022，Vol.14Issue(10)：83-94,12.

CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant

Chenshuo Wu ¹Xiaopeng Ma ²Omar A.Al-Hartomy ³S.Wageh ³Abdullah G.Al-Sehemi ⁴Zhiguang Luo ⁵Yaqing He ⁶Jingfeng Li ⁷Zhongjian Xie ¹Han Zhang ⁸Zhi Chen ⁸Chaozhou Li ⁹Yabin Hao ¹Yuxuan Tang ¹Yuxuan Yuan ¹⁰Luxiao Chai ¹Taojian Fan ¹Jiangtian Yu¹¹

作者信息

1. International Collaborative Laboratory of 2D,Materials for Optoelectronics Science and Technology of Ministry of Education,Institute of Microscale Optoelectronics,College of Physics and Optoelectronic Engineering,Shenzhen University,Shenzhen 518060,People's Republic of China
2. Department of Respiratory,Shenzhen Children's Hospital,Shenzhen 518038,People's Republic of China
3. Department of Physics,Faculty of Science,King Abdulaziz University,Jeddah 21589,Saudi Arabia
4. Research Center for Advanced Materials Science(RCAMS),King Khalid University,P.O.Box 9004,Abha 61413,Saudi Arabia
5. Department of Chemistry,College of Science,King Khalid University,P.O.Box 9004,Abha 61413,Saudi Arabia
6. Zhongmin(Shenzhen)Intelligent Ecology Co.,Ltd,Shenzhen 518055,People's Republic of China
7. Shenzhen Center for Disease Control and Prevention,Shenzhen 518055,People's Republic of China
8. Shenzhen International Institute for Biomedical Research,Shenzhen 518116,People's Republic of China
9. Institute of Pediatrics,Shenzhen Children's Hospital,Shenzhen 518038,People's Republic of China
10. Hospital of Guangzhou Medical University,Qingyuan city People's Hospital,Qingyuan 511518,People's Republic of China
11. Shenzhen Han's Tech Limited Company,Shenzhen 518000,People's Republic of China
折叠

摘要

关键词

SARS-COV-2 variant/Methodology of electrochemical CRISPR sensing(MOECS)/Gold nanoparticles(AuNPs)/Point-of-care testing(POCT)

Key words

SARS-COV-2 variant/Methodology of electrochemical CRISPR sensing(MOECS)/Gold nanoparticles(AuNPs)/Point-of-care testing(POCT)

引用本文复制引用

Chenshuo Wu,Xiaopeng Ma,Omar A.Al-Hartomy,S.Wageh,Abdullah G.Al-Sehemi,Zhiguang Luo,Yaqing He,Jingfeng Li,Zhongjian Xie,Han Zhang,Zhi Chen,Chaozhou Li,Yabin Hao,Yuxuan Tang,Yuxuan Yuan,Luxiao Chai,Taojian Fan,Jiangtian Yu..CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant[J].纳微快报（英文）,2022,14(10):83-94,12.

基金项目

The authors are grateful to the financial support from the Innovation Team Project of Department of Edu-cation of Guangdong Province(No.2018KCXTD026),Guang-dong Scientific and Technological Project(2019B1515120043,2020A151501612,2021A1515220109,2022B1515020093),Science and Technology Innovation Commission of Shenzhen(Grant No.KCXFZ20201221173413038),and Longhua District Science and Innovation Commission Project Grants of Shenzhen(JCYJ201904).Open access funding provided by Shanghai Jiao Tong University. （No.2018KCXTD026）

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