Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model
Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model
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Jennifer Zieba,Kimberly N.Forlenza,Kelly Heard,Jorge H.Martin,Michaela Bosakova,Daniel H.Cohn,Stephen P.Robertson,Pavel Krejci,Deborah Krakow..Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model[J].骨研究(英文版),2022,10(3):524-535,12.基金项目
This work was supported by F31 AR066487(JZ)and R01 AR066124(DK).We also thank the March of Dimes(http://www.marchofdimes.org)and the Joseph Drown Foundation(http://www.jdrown.org)for their support with DK.We are grateful to the CNSI Advanced Light Microscopy/Spectroscopy Shared Resource Facility at UCLA,supported with funding from NIH-NCRR shared resources grant(CJX1-443835-WS-29646),and NSF Major Research Instrumentation grant(CHE-0722519),for their assistance.The research was supported by the NIH/National Center for Advancing Translational Science(NCATS)UCLA CTSI Grant Number UL1TR000124 and by the NIH/National Institute of Arthritis Musculoskeletal and Skin(NIAMS).PK was supported by the Ministry of Education,Youth and Sports of the Czech Republic(LTAUSA19030),and the Agency for Health care Research of the Czech Republic(NV18-08-00567).The funders had no role in the study design,data collection and analysis,decision to publish,or preparation of the manuscript. (JZ)