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首页|期刊导航|骨研究(英文版)|Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Jennifer Zieba Kimberly N.Forlenza Kelly Heard Jorge H.Martin Michaela Bosakova Daniel H.Cohn Stephen P.Robertson Pavel Krejci Deborah Krakow

骨研究(英文版)2022,Vol.10Issue(3):524-535,12.
骨研究(英文版)2022,Vol.10Issue(3):524-535,12.

Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Jennifer Zieba 1Kimberly N.Forlenza 1Kelly Heard 1Jorge H.Martin 1Michaela Bosakova 2Daniel H.Cohn 3Stephen P.Robertson 4Pavel Krejci 1Deborah Krakow5

作者信息

  • 1. Department of Orthopedic Surgery,Los Angeles,CA 90095,USA
  • 2. Department of Biology,Faculty of Medicine,Masaryk University,62500 Brno,Czech Republic
  • 3. International Clinical Research Center,St.Anne's University Hospital,65691 Brno,Czech Republic
  • 4. Institute of Animal Physiology and Genetics,Czech Academy of Sciences,60200 Brno,Czech Republic
  • 5. Department of Molecular Cell and Developmental Biology,University of California,Los Angeles,Los Angeles,CA 90095,USA
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摘要

引用本文复制引用

Jennifer Zieba,Kimberly N.Forlenza,Kelly Heard,Jorge H.Martin,Michaela Bosakova,Daniel H.Cohn,Stephen P.Robertson,Pavel Krejci,Deborah Krakow..Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model[J].骨研究(英文版),2022,10(3):524-535,12.

基金项目

This work was supported by F31 AR066487(JZ)and R01 AR066124(DK).We also thank the March of Dimes(http://www.marchofdimes.org)and the Joseph Drown Foundation(http://www.jdrown.org)for their support with DK.We are grateful to the CNSI Advanced Light Microscopy/Spectroscopy Shared Resource Facility at UCLA,supported with funding from NIH-NCRR shared resources grant(CJX1-443835-WS-29646),and NSF Major Research Instrumentation grant(CHE-0722519),for their assistance.The research was supported by the NIH/National Center for Advancing Translational Science(NCATS)UCLA CTSI Grant Number UL1TR000124 and by the NIH/National Institute of Arthritis Musculoskeletal and Skin(NIAMS).PK was supported by the Ministry of Education,Youth and Sports of the Czech Republic(LTAUSA19030),and the Agency for Health care Research of the Czech Republic(NV18-08-00567).The funders had no role in the study design,data collection and analysis,decision to publish,or preparation of the manuscript. (JZ)

骨研究(英文版)

OACSCDSCI

2095-4700

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