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Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation

Peng Ding Qiyuan Tan Zhanying Wei Qiyu Chen Chun Wang Luyue Qi Li Wen Changqing Zhang Chen Yao

骨研究（英文版）2022，Vol.10Issue(3)：594-614,21.

Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation

Peng Ding ¹Qiyuan Tan ²Zhanying Wei ³Qiyu Chen ¹Chun Wang ³Luyue Qi ⁴Li Wen ⁵Changqing Zhang ¹Chen Yao¹

作者信息

1. Department of Orthopedic Surgery,Shanghai Jiaotong University affiliated Sixth People's Hospital,Shanghai,China
2. Department of Endocrinology and Metabolism,Shanghai Jiaotong University affiliated Sixth People's Hospital,Shanghai,China
3. Department of Osteoporosis and Skeletal Disorders,Shanghai Jiaotong University affiliated Sixth People's Hospital,Shanghai,China
4. Department of Endocrinology and Metabolism,Second Affiliated Hospital of Soochow University,Suzhou,China
5. Section of Endocrinology,Department of Internal Medicine,Yale University School of Medicine,New Haven,USA
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摘要

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Peng Ding,Qiyuan Tan,Zhanying Wei,Qiyu Chen,Chun Wang,Luyue Qi,Li Wen,Changqing Zhang,Chen Yao..Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation[J].骨研究（英文版）,2022,10(3):594-614,21.

基金项目

This work was supported by grants from the National Natural Science Foundation of China(nos.81820100820 and 81372845 to C.Z. （）

no.81400855 to C.Y.and no.82170893 to Q.T.).This work was also supported by National Key R&D Program of China grant no.2018YFC1106300(to C.Z.),Natural Science Foundation of Shanghai grant no.21ZR1448600(to C.Y.)and Science and Technology Commission of Shanghai Municipality grant no.14pj1407200(to C.Y.). （to C.Z.）

骨研究（英文版）

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ISSN：2095-4700

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