18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs
Qian Zhang Liwei Gu Jiahao Li Qiuyan Guo Chuanbin Yang Yin Kwan Wong Fei Xia Jigang Wang Piao Luo Liuhai Zheng Jiayun Chen Junzhe Zhang Huan Tang Dandan Liu Xueling He Qiaoli Shi
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs
摘要
关键词
Glycyrrhetinic acid/Hepatic fibrosis/Peroxiredoxin/Reactive oxygen species/ApoptosisKey words
Glycyrrhetinic acid/Hepatic fibrosis/Peroxiredoxin/Reactive oxygen species/Apoptosis引用本文复制引用
Qian Zhang,Liwei Gu,Jiahao Li,Qiuyan Guo,Chuanbin Yang,Yin Kwan Wong,Fei Xia,Jigang Wang,Piao Luo,Liuhai Zheng,Jiayun Chen,Junzhe Zhang,Huan Tang,Dandan Liu,Xueling He,Qiaoli Shi..18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs[J].药物分析学报(英文),2022,12(4):570-582,13.基金项目
The authors gratefully acknowledge the financial support from the Innovation Team and Talents Cultivation Program of the Na-tional Administration of Traditional Chinese Medicine,China(Grant No.:ZYYCXTD-C-202002),the National Key Research and Devel-opment Program of China,China(Grant No.:2020YFA0908000),the National Natural Science Foundation of China,China(Grant Nos.:81803389,81903588,32101219,81702580,82074098,81903866,and 81803456),and the Fundamental Research Funds for the Central Public Welfare Research Institutes,China(Grant Nos.:ZZ14-YQ-050,ZZ14-YQ-059,ZZ15-ND-10,ZZ15-YQ-063,ZZ14-ND-010,and ZZ14-FL-002). (Grant No.:ZYYCXTD-C-202002)