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Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS

Nikita Looby Anna Roszkowska Aadil Ali Barbara Bojko Marcelo Cypel Janusz Pawliszyn

药物分析学报(英文)2022,Vol.12Issue(4):590-600,11.
药物分析学报(英文)2022,Vol.12Issue(4):590-600,11.

Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS

Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS

Nikita Looby 1Anna Roszkowska 1Aadil Ali 2Barbara Bojko 3Marcelo Cypel 4Janusz Pawliszyn3

作者信息

  • 1. Department of Chemistry,University of Waterloo,Waterloo,N2L 3G1,Canada
  • 2. Department of Pharmaceutical Chemistry,Medical University of Gdansk,80-416,Gdansk,Poland
  • 3. Division of Thoracic Surgery,University Health Network,Toronto,M5G 2C4,Canada
  • 4. Department of Pharmacodynamics and Molecular Pharmacology,Faculty of Pharmacy,Collegium Medicum in Bydgoszcz,Nicolaus Copernicus University in Torun,85-089,Bydgoszcz,Poland
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摘要

关键词

Normothermic ex vivo lung perfusion/Solid phase microextraction/Lung metabolomics

Key words

Normothermic ex vivo lung perfusion/Solid phase microextraction/Lung metabolomics

引用本文复制引用

Nikita Looby,Anna Roszkowska,Aadil Ali,Barbara Bojko,Marcelo Cypel,Janusz Pawliszyn..Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS[J].药物分析学报(英文),2022,12(4):590-600,11.

基金项目

We would like to thank our collaborators at Millipore Sigma for providing us with the SPME fibers.We are grateful to the Canadian Institute of Health Research(CIHR)-Natural Sciences and Engineering Research Council(NSERC)of the Canada Collaborative Health Research Projects program for their finan-cial support(Grant No.:355935)and the Natural Sciences and Engineering Research Council of Canada Industrial Research Chair(IRC)program. (CIHR)

药物分析学报(英文)

OACSCDSCI

2095-1779

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