Enzyme-linked immunosorbent assays for quantification of MMMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera
Min Pei Xiaorong Tan Xiaoyue Liu Peng Zhu Yongzhen Liu Deheng Wang Junliang Wu Qi Wang Guifeng Wang Likun Gong Qiuping Qin Tingting Liu Chunhe Wang Lu Ouyang Jianhua Sun Xiaojie Deng Xiaomin Sun Wei Wu Peng Huang Yi-Li Chen
Enzyme-linked immunosorbent assays for quantification of MMMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera
Enzyme-linked immunosorbent assays for quantification of MMMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera
摘要
关键词
Monomethyl auristatin E/Antibody-drug conjugates/Pharmacokinetics/Trophoblast cell surface antigen 2Key words
Monomethyl auristatin E/Antibody-drug conjugates/Pharmacokinetics/Trophoblast cell surface antigen 2引用本文复制引用
Min Pei,Xiaorong Tan,Xiaoyue Liu,Peng Zhu,Yongzhen Liu,Deheng Wang,Junliang Wu,Qi Wang,Guifeng Wang,Likun Gong,Qiuping Qin,Tingting Liu,Chunhe Wang,Lu Ouyang,Jianhua Sun,Xiaojie Deng,Xiaomin Sun,Wei Wu,Peng Huang,Yi-Li Chen..Enzyme-linked immunosorbent assays for quantification of MMMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera[J].药物分析学报(英文),2022,12(4):645-652,8.基金项目
This work was supported by the China National Major Scientific and Technological Special Project for"Significant New Drugs Innovation and Development"(Grant No.:2019ZX09732002-006),the National New Drug Creation Program of China(Grant No.:2018ZX09201017-004),the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant Nos.:XDA12020223,XDA12020330,XDA12020360,and XDA12050305),the National Natural Science Foundation of China(Grant Nos.:81872785 and 81673347),the Science and Technology Planning Projects of Department of Science and Technology Province(Grant No.:20190202),Shanghai Municipal Commission of Science and Tech-nology of China(Grant Nos.:17431904400,19YF1457400,and 21S11904500),Institutes for Drug Discovery and Development,the Chinese Academy of Sciences(Grant Nos.:CASIMM0120202007 and CASIMM0120202008),and Major Scientific and Technological Special Project of Zhongshan City(Grant Nos.:191022172638719 and 210205143867019). (Grant No.:2019ZX09732002-006)