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Design,synthesis,and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors

Yuan-Yuan Hei Si Wang Xiao-Xiao Xi Hai-Peng Wang Yuanxu Guo Minhang Xin Congshan Jiang Shemin Lu San-Qi Zhang

药物分析学报（英文）2022，Vol.12Issue(4)：653-663,11.

Design,synthesis,and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors

Yuan-Yuan Hei ¹Si Wang ²Xiao-Xiao Xi ³Hai-Peng Wang ²Yuanxu Guo ¹Minhang Xin ⁴Congshan Jiang ³Shemin Lu ²San-Qi Zhang¹

作者信息

1. Department of Medicinal Chemistry,School of Pharmacy,Xi'an Jiaotong University Health Science Center,Xi'an,710061,China
2. Key Laboratory of Environment and Genes Related to Diseases(Xi'an Jiaotong University),Ministry of Education,Xi'an,710061,China
3. Institute of Molecular and Translational Medicine(IMTM),and Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Xi'an Jiaotong University Health Science Center,Xi'an,710061,China
4. Department of Medical Oncology,Shaanxi Provincial People's Hospital,Xi'an,710068,China
折叠

摘要

关键词

Quinolone derivatives/Small-molecule miRNA-21 inhibitor/Antitumor agent/Drug design

Key words

Quinolone derivatives/Small-molecule miRNA-21 inhibitor/Antitumor agent/Drug design

引用本文复制引用

Yuan-Yuan Hei,Si Wang,Xiao-Xiao Xi,Hai-Peng Wang,Yuanxu Guo,Minhang Xin,Congshan Jiang,Shemin Lu,San-Qi Zhang..Design,synthesis,and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors[J].药物分析学报（英文）,2022,12(4):653-663,11.

基金项目

Financial support from the National Natural Science Foundation of China(Grant No.:81673354)is gratefully acknowledged. （Grant No.:81673354）

药物分析学报（英文）

OACSCDSCI

ISSN：2095-1779

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