Deficiency of transmembrane AMPA receptor regulatory protein γ-8 leads to attention-deficit hyperactivity disorder-like behavior in miceOACSCDCSTPCD
Attention-deficit hyperactivity disorder(ADHD) is a neurodevelopmental disorder prevalent in schoolage children. At present, however, its etiologies and risk factors are unknown. Transmembrane α-amino-3-hydroxy-5-methyl-4-iso…查看全部>>
Wan-Jun Bai;Xing-Guang Luo;Bao-Hua Jin;Kang-Sheng Zhu;Wen-Yan Guo;Xiao-Que Zhu;Xia Qin;Zu-Xiao Yang;Jiao-Jiao Zhao;Si-Ruan Chen;Ri Wang;Jie Hao;Fei Wang;Yun Stone Shi;De-Zhi Kong;Wei Zhang
Department of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,China Department of Pharmacy,Hebei General Hospital,Shijiazhuang,Hebei 050051,ChinaBeijing Huilongguan Hospital,Peking University Huilongguan School of Clinical Medicine,Beijing 100096,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,China Fourth Hospital of Hebei Medical University,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Psychiatry,Affiliated Nanjing Brain Hospital,Nanjing Medical University,Nanjing,Jiangsu 210029,ChinaState Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animal for Disease Study,Model Animal Research Center,Nanjing University,Nanjing,Jiangsu 210061,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,ChinaDepartment of Pharmacology,Institution of Chinese Integrative Medicine,Key Laboratory of Neural and Vascular Biology,Ministry of Education,Key Laboratory of New Drug Pharmacology and Toxicology,Hebei Medical University,Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang,Hebei 050017,China
临床医学
Attention-deficit hyperactivity disorderTARPγ-8MethylphenidateProteomicsPhenome-wide association study
《动物学研究(英文)》 2022 (5)
P.851-870,20
supported by the National Natural Science Foundation of China (81872848, 81803509)National Major Special Project on New Drug Innovation grant(2018ZX09711001-004-003)CAMS Innovation Fund for Medical Sciences (2019-I2M-5-055)Hebei Natural Science Foundation(H2019206038)National Key R&D Program of China(2019YFA0801603)Natural Science Foundation of Jiangsu Province (BE2019707)。
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