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Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip

Jun Xu Qing Tang Runhui Zhang Haoyi Chen Bee Luan Khoo Xinguo Zhang Yue Chen Hong Yan Jincheng Li Huaze Shao Lihong Liu

药物分析学报：英文版2022，Vol.12Issue(5)：P.808-813,6.

药物分析学报：英文版2022，Vol.12Issue(5)：P.808-813,6.DOI:10.1016/j.jpha.2022.05.009

Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip

Jun Xu ¹Qing Tang ¹Runhui Zhang ¹Haoyi Chen ²Bee Luan Khoo ³Xinguo Zhang ¹Yue Chen ¹Hong Yan ¹Jincheng Li ¹Huaze Shao ¹Lihong Liu¹

作者信息

1. NMPA Key Laboratory for Research and Evaluation of Drug Metabolism,Guangdong Provincial Key Laboratory of New Drug Screening,School of Pharmaceutical Sciences,Southern Medical University,Guangzhou,510515,China
2. The Second Clinical Medical School,Southern Medical University,Guangzhou,510515,China
3. Department of Biomedical Engineering,City University of Hong Kong,Hong Kong,999077,China
折叠

摘要

关键词

MicroRNAs/Microfluidic chip/Electrokinetic signal amplification/Polyadenine-DNA/Gold nanoparticle

分类

医药卫生

引用本文复制引用

Jun Xu,Qing Tang,Runhui Zhang,Haoyi Chen,Bee Luan Khoo,Xinguo Zhang,Yue Chen,Hong Yan,Jincheng Li,Huaze Shao,Lihong Liu..Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip[J].药物分析学报：英文版,2022,12(5):P.808-813,6.

基金项目

supported financially by the National Natural Science Foundation of China(Grant No.:81973282) （Grant No.:81973282）

Guangdong Basic and Applied Basic Research Foundation(Grant Nos.:2018A030313843 and 2021A1515011493) （Grant Nos.:2018A030313843 and 2021A1515011493）

National College Students Innovation and Entrepreneurship Training Program(Grant No.:202012121024) （Grant No.:202012121024）

Science and Technology Innovation Strategic Special Project of Guangdong Province("Climbing Program"Special Project （）

GrantNo.:pdjh2022b0106) （）

Guangdong College Students Innovation and Entrepreneurship Training Program(Grant No.:S202112121154). （Grant No.:S202112121154）

药物分析学报：英文版

OACSCDSCI

ISSN：2095-1779

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