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Chronic lithium treatment ameliorates ketamine-induced mania-like behavior via the PI3K-AKT signaling pathway

Rong-Jun Ni Tian-Hao Gao Yi-Yan Wang Yang Tian Jin-Xue Wei Lian-Sheng Zhao Pei-Yan Ni Xiao-Hong Ma Tao Li

动物学研究(英文)2022，Vol.43Issue(6)：P.989-1004,16.

动物学研究(英文)2022，Vol.43Issue(6)：P.989-1004,16.DOI:10.24272/j.issn.2095-8137.2022.278

Chronic lithium treatment ameliorates ketamine-induced mania-like behavior via the PI3K-AKT signaling pathway

Rong-Jun Ni ¹Tian-Hao Gao ¹Yi-Yan Wang ¹Yang Tian ¹Jin-Xue Wei ¹Lian-Sheng Zhao ¹Pei-Yan Ni ¹Xiao-Hong Ma ¹Tao Li²

作者信息

1. Psychiatric Laboratory and Mental Health Center,West China Hospital of Sichuan University,Chengdu,Sichuan 610041,China
2. Affiliated Mental Health Center&Hangzhou Seventh People’s Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310013,China NHC and CAMS Key Laboratory of Medical Neurobiology,MOE Frontier Science Center for Brain Science and Brain-machine Integration,School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou,Zhejiang 310014,China Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence,Guangzhou,Guangdong 510799,China
折叠

摘要

关键词

Lithium/Ketamine/Medial prefrontal cortex/Bipolar disorder/Manic/PI3K-AKT signaling pathway

分类

医药卫生

引用本文复制引用

Rong-Jun Ni,Tian-Hao Gao,Yi-Yan Wang,Yang Tian,Jin-Xue Wei,Lian-Sheng Zhao,Pei-Yan Ni,Xiao-Hong Ma,Tao Li..Chronic lithium treatment ameliorates ketamine-induced mania-like behavior via the PI3K-AKT signaling pathway[J].动物学研究(英文),2022,43(6):P.989-1004,16.

基金项目

supported by the Key Project of the National Natural Science Foundation of China(81920108018 to T.L.and P.S.) （81920108018 to T.L.and P.S.）

Ministry of Science and Technology of the People’s Republic of China(2022ZD0205200) （2022ZD0205200）

Natural Science Foundation of Sichuan Province(2022NSFSC1607) （2022NSFSC1607）

Key R&D Program of Zhejiang(2022C03096 to T.L.) （2022C03096 to T.L.）

Special Foundation for Brain Research from Science and Technology Program of Guangdong(2018B030334001) （2018B030334001）

Project for Hangzhou Medical Disciplines of Excellence&Key Project for Hangzhou Medical Disciplines （）

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动物学研究(英文)

OACSCDCSTPCD

ISSN：2095-8137

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