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Cellular response to β- amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

Haolin Zhang Xianghua Li Xiaoli Wang Jiayu Xu Felice Elefant Juan Wang

动物模型与实验医学(英文)2023,Vol.6Issue(1):3-9,7.
动物模型与实验医学(英文)2023,Vol.6Issue(1):3-9,7.DOI:10.1002/ame2.12313

Cellular response to β- amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

Cellular response to β- amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

Haolin Zhang 1Xianghua Li 1Xiaoli Wang 1Jiayu Xu 1Felice Elefant 2Juan Wang1

作者信息

  • 1. Faculty of Environment and Life,Beijing University of Technology,Beijing,China
  • 2. Department of Biology,Drexel University,Philadelphia,Pennsylvania,USA
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摘要

关键词

Alzheimer's disease (AD)/astrocytes/endopeptidase/glutaminyl cyclase (QC)/microglia/p75 neurotrophin receptor (p75NTR)/proteolysis targeting chimeras (PROTACs)/β- Amyloid (Aβ)

Key words

Alzheimer's disease (AD)/astrocytes/endopeptidase/glutaminyl cyclase (QC)/microglia/p75 neurotrophin receptor (p75NTR)/proteolysis targeting chimeras (PROTACs)/β- Amyloid (Aβ)

引用本文复制引用

Haolin Zhang,Xianghua Li,Xiaoli Wang,Jiayu Xu,Felice Elefant,Juan Wang..Cellular response to β- amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics[J].动物模型与实验医学(英文),2023,6(1):3-9,7.

基金项目

National Institute of Neurological Disorders and Stroke,Grant/Award Number:2RF1NS095799 ()

National Natural Science Foundation of China,Grant/Award Number:31970044 and 91854115 ()

Beijing University of Technology Faculty of Environment and Life Seed Funding,Grant/Award Number:049000513202 ()

动物模型与实验医学(英文)

OACSCD

2096-5451

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