无机材料学报2023，Vol.38Issue(1)：43-54,12.DOI:10.15541/jim20220578
纳米酶:一种抗微生物感染新方法
Nanozyme: a New Approach for Anti-microbial Infections
摘要
Abstract
Bacteria and viruses always posed a threat to human health. Most impressively, SARS-CoV-2 has raged around the world for almost three years, causing huge loss to human health. Facing increasing challenges of drug-resistance and poor treatment efficacy, new solutions are urgently needed to combat pathogenic microorganisms. Recently, nanozymes with intrinsic enzyme-like activities emerged as a promising new type of "antibiotics". Nanozymes exhibit superior antibacterial and antiviral activities under physiological conditions by efficiently catalyzing generation of a large number of reactive oxygen species. Moreover, enhanced therapeutic effects are achieved in nanozyme-based therapy aided by the unique physicochemical properties of nanomaterials such as photothermal and photodynamic effects. This paper reviews the latest research progress in the field of anti-microbial nanozymes, systematically summarizes and analyzes the principles of nanozymes in the treatment of bacteria and viruses from a mechanistic point of view. An outlook on the future direction and the challenges of new anti-microbial infection nanomaterials are proposed to provide inspiration for developing next generation anti-microbial nanozymes.关键词
纳米酶/抗微生物/催化/抗菌/抗病毒/综述Key words
nanozyme/anti-microbial/catalyze/antibacterial/antivirus/review分类
化学化工引用本文复制引用
吴雪彤,张若飞,阎锡蕴,范克龙..纳米酶:一种抗微生物感染新方法[J].无机材料学报,2023,38(1):43-54,12.基金项目
CAS Interdisciplinary Innovation Team(JCTD-2020-08) （JCTD-2020-08）
Youth Innovation Promotion Association of Chinese Academy of Sciences(2019093) （2019093）
