The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway
Zhiqi Li Jiarui Wu Shengyun Dai Ruichao Lin Chongjun Zhao Qiqi Fan Meilin Chen Ying Dong Farong Li Mingshuang Wang Yulin Gu Simin Guo Xianwen Ye
The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway
The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway
摘要
关键词
Polyphyllin Ⅰ/Polyphyllin Ⅱ/Zebrafish/Hepatotoxicity/SQLEKey words
Polyphyllin Ⅰ/Polyphyllin Ⅱ/Zebrafish/Hepatotoxicity/SQLE引用本文复制引用
Zhiqi Li,Jiarui Wu,Shengyun Dai,Ruichao Lin,Chongjun Zhao,Qiqi Fan,Meilin Chen,Ying Dong,Farong Li,Mingshuang Wang,Yulin Gu,Simin Guo,Xianwen Ye..The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway[J].药物分析学报（英文）,2023,13(1):39-54,16.基金项目
We are grateful to the Beijing Key Laboratory of Traditional Chinese Medicine Quality Evaluation for providing experimental instruments and equipment.We thank Beijing University of Chi-nese Medicine for providing the laboratory platform.The authors would like to express their gratitude to Edit Springs(https://www.editsprings.cn/)for the expert linguistic services provided.This work was supported by the National Natural Science Foundation of China(Grant No.:82204753),the Scientific Research Staring Foundation for the New Teachers of Beijing University of Chinese Medicine(Grant No.:2020-JYB-XJSJJ-009),and Special Scientific Research for Traditional Chinese Medicine of State Administration of Traditional Chinese Medicine of China(Grant No.:201507004).The funders had no role in the study design,data collection,data analysis,interpretation,or writing of the report. （https://www.editsprings.cn/）
