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首页|期刊导航|中华医学杂志(英文版)|Connexin 43-modified bone marrow stromal cells reverse the imatinib resistance of K562 cells via Ca2+-dependent gap junction intercellular communication

Connexin 43-modified bone marrow stromal cells reverse the imatinib resistance of K562 cells via Ca2+-dependent gap junction intercellular communication

Xiaoping Li Xi Zhang Yunshuo Xiao Xiaoqi Wang Ruihao Huang Rui Wang Yi Deng Jun Rao Qiangguo Gao Shijie Yang

中华医学杂志(英文版)2023,Vol.136Issue(2):194-206,13.
中华医学杂志(英文版)2023,Vol.136Issue(2):194-206,13.DOI:10.1097/CM9.0000000000002554

Connexin 43-modified bone marrow stromal cells reverse the imatinib resistance of K562 cells via Ca2+-dependent gap junction intercellular communication

Connexin 43-modified bone marrow stromal cells reverse the imatinib resistance of K562 cells via Ca2+-dependent gap junction intercellular communication

Xiaoping Li 1Xi Zhang 2Yunshuo Xiao 3Xiaoqi Wang 3Ruihao Huang 3Rui Wang 3Yi Deng 3Jun Rao 3Qiangguo Gao 4Shijie Yang3

作者信息

  • 1. Department of Hematology,920th Hospital of Joint Logistic Support Force of People's Liberation,Kunming,Yunnan 650000,China
  • 2. Medical Center of Hematology,Xinqiao Hospital,State Key Laboratory of Trauma,Burn and Combined Injury,Army Medical University,Chongqing 400037,China||Jinfeng Laboratory,Chongqing 401329,China
  • 3. Medical Center of Hematology,Xinqiao Hospital,State Key Laboratory of Trauma,Burn and Combined Injury,Army Medical University,Chongqing 400037,China
  • 4. Department of Cell Biology College of Basic Medicine,Army Medical University,Chongqing 400038,China
  • 折叠

摘要

关键词

Bone marrow microenvironment/Connexin 43(Cx43)/Gap junction intercellular communication/Hypoxia/Imatinib resistance

Key words

Bone marrow microenvironment/Connexin 43(Cx43)/Gap junction intercellular communication/Hypoxia/Imatinib resistance

引用本文复制引用

Xiaoping Li,Xi Zhang,Yunshuo Xiao,Xiaoqi Wang,Ruihao Huang,Rui Wang,Yi Deng,Jun Rao,Qiangguo Gao,Shijie Yang..Connexin 43-modified bone marrow stromal cells reverse the imatinib resistance of K562 cells via Ca2+-dependent gap junction intercellular communication[J].中华医学杂志(英文版),2023,136(2):194-206,13.

基金项目

This work was supported by the National Key R&D Program of China(2022YFA1103300),the National Natural Science Foundation of China(81873424,81570097),the Natural Science Foundation of Chongqing Innovation Group Science Program(cstc2021jcyj-cxttX0001),Clinical Medical Research Project of Army Medical University(2018XLC1006),and Translational Research Grant of NCRCH(2020ZKZC02). (2022YFA1103300)

中华医学杂志(英文版)

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