数字中医药（英文）2023，Vol.6Issue(1)：9-27,19.DOI:10.1016/j.dcmed.2023.02.001
功能性食品及药食同源产品中抗抑郁活性成分及其作用机制
Antidepressant-like active ingredients and their related mechanisms of functional foods or medicine and food homologous products
摘要
Abstract
Objective To provide a new idea for the treatment of depression by summarizing the antide-pressant effect and mechanism of active ingredients in functional food,and medicine and food homologous products.Methods The literature related to the antidepressant of functional food or medicine and food homologous products from September 25,1996 to September 5,2022 was collected through PubMed,Google Academic,Web of Science,and China National Knowledge Infrastructure(CNKI)databases.After that,their antidepressant active ingredients and mechanism of ac-tion were systematically summarized and analyzed.Results A total of 146 pieces of literature were involved in the study,including 67 plant-de-rived functional foods or medicine and food homologous products,32 antidepressant ex-tracts(including 8 flavonoid extracts),and 87 antidepressant active ingredients.The 87 anti-depressant active ingredients include 7 terpenes,22 saponins,15 flavonoids,11 phenylpro-panoids,7 phenols,6 sugars,8 alkaloids,and 11 others.Conclusion The study summarized and analyzed the active ingredients and mechanisms of antidepressants in functional foods and medicine and food homologous products,which provides a new vision for the development of new antidepressants and a potential alternative treatment for patients with depression.关键词
抗抑郁/药食同源/功能性食品/提取物/活性成分/中医药Key words
Antidepressant/Medicine and food homologous/Functional food/Extract/Active ingredients/Traditional Chinese medicine(TCM)引用本文复制引用
叶恬,徐梦涛,方景鹏,吴沁璇,邹小艳,颜昉芩,卿志星..功能性食品及药食同源产品中抗抑郁活性成分及其作用机制[J].数字中医药（英文）,2023,6(1):9-27,19.基金项目
National Key Rearch and Development Program of China(2021YFD1600301),Scientific Research Cooperation Project of Datong Daylily Industial Development Re-search Institute(2022QT003-3),Hunan Provincial Natur-al Science Foundation of China(2021JJ40245),Hong Kong Scholars Program(2021-164),and Hunan Provin-cial Key Research and Development Project(2020NK2031). （2021YFD1600301）
