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首页|期刊导航|药物分析学报(英文)|Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins

Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins

Chi Soo Park Ha Hyung Kim Minju Kang Ahyeon Kim Chulmin Moon Mirae Kim Jieun Kim Subin Yang Leeseul Jang Ji Yeon Jang

药物分析学报(英文)2023,Vol.13Issue(3):305-314,10.
药物分析学报(英文)2023,Vol.13Issue(3):305-314,10.

Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins

Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins

Chi Soo Park 1Ha Hyung Kim 1Minju Kang 1Ahyeon Kim 1Chulmin Moon 1Mirae Kim 1Jieun Kim 1Subin Yang 1Leeseul Jang 1Ji Yeon Jang1

作者信息

  • 1. Department of Global Innovative Drugs,Graduate School ofChung-Ang University,Seoul,06974,Republic of Korea
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摘要

关键词

Therapeutic glycoprotein/Sialylation/Linkage isomer/LC-MS/MS

Key words

Therapeutic glycoprotein/Sialylation/Linkage isomer/LC-MS/MS

引用本文复制引用

Chi Soo Park,Ha Hyung Kim,Minju Kang,Ahyeon Kim,Chulmin Moon,Mirae Kim,Jieun Kim,Subin Yang,Leeseul Jang,Ji Yeon Jang..Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins[J].药物分析学报(英文),2023,13(3):305-314,10.

基金项目

This study was supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF)and funded by the Ministry of Education,Korea(Grant No.:2021R1A6A1A03044296).This study was supported by the Chung-Ang University Graduate Research Scholarship in 2022. (NRF)

药物分析学报(英文)

OACSCD

2095-1779

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