动物学研究(英文)2023，Vol.44Issue(3)：P.451-466,16.DOI:10.24272/j.issn.2095-8137.2023.031
Cell atlas of CCl_(4)-induced progressive liver fibrosis reveals stage-specific responses
Peng-Cheng Guo 1Jing Zuo 2Ke-Ke Huang 3Guang-Yao Lai 4Xiao Zhang 1Juan An 5Jin-Xiu Li 6Li Li 7Liang Wu 7Yi-Ting Lin 7Dong-Ye Wang 7Jiang-Shan Xu 2Shi-Jie Hao 6Yang Wang 2Rong-Hai Li 2Wen Ma 2Yu-Mo Song 2Chang Liu 2Chuan-Yu Liu 2Zhen Dai 8Yan Xu 9Amar Deep Sharma 10Michael Ott 10Qing Ou-Yang 11Feng Huo 11Rong Fan 12Yong-Yin Li 12Jin-Lin Hou 12Giacomo Volpe 13Long-Qi Liu 2Miguel A.Esteban 14Yi-Wei Lai2
作者信息
- 1. State Key Laboratory for Zoonotic Diseases,Key Laboratory for Zoonosis Research of Ministry of Education,Institute of Zoonosis,College of Veterinary Medicine,Jilin University,Changchun,Jilin 130062,China BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China
- 2. BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China
- 3. Key Laboratory of Biological Targeting Diagnosis,Therapy and Rehabilitation of Guangdong Higher Education Institutes,Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510799,China
- 4. BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China Laboratory of Integrative Biology,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China Joint School of Life Sciences,Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University,Guangzhou,Guangdong 510530,China
- 5. BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China Laboratory of Integrative Biology,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China School of Life Sciences,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230026,China
- 6. BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China
- 7. Laboratory of Integrative Biology,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China
- 8. Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China
- 9. Biotherapy Centre,Third Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong 510630,China
- 10. Department of Gastroenterology,Hepatology and Endocrinology,Hannover Medical School,Hannover 30625,Germany
- 11. Department of Hepatobiliary Surgery and Liver Transplant Center,General Hospital of Southern Theater Command,Guangzhou,Guangdong 510010,China
- 12. Department of Infectious Diseases,Nanfang Hospital,Southern Medical University,Guangdong Provincial Key Laboratory of Viral Hepatitis Research,Guangzhou,Guangdong 510515,China
- 13. Hematology and Cell Therapy Unit,IRCCS-Istituto Tumori‘Giovanni Paolo II’,Bari 70124,Italy
- 14. State Key Laboratory for Zoonotic Diseases,Key Laboratory for Zoonosis Research of Ministry of Education,Institute of Zoonosis,College of Veterinary Medicine,Jilin University,Changchun,Jilin 130062,China BGI-Hangzhou,Hangzhou,Zhejiang 310012,China BGI-Shenzhen,Shenzhen,Guangdong 518083,China Key Laboratory of Biological Targeting Diagnosis,Therapy and Rehabilitation of Guangdong Higher Education Institutes,Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510799,China Laboratory of Integrative Biology,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China Joint School of Life Sciences,Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University,Guangzhou,Guangdong 510530,China Institute of Experimental Hematology,Hannover Medical School,Hannover 30625,Germany
- 折叠
摘要
关键词
Liver fibrosis/Toxicity/Single-cell and single-nucleus RNA-sequencing/Hepatocytes/Hepatic stellate cells/Angiogenesis/Cell-cell interactions/Gene regulatory networks分类
医药卫生引用本文复制引用
Peng-Cheng Guo,Jing Zuo,Ke-Ke Huang,Guang-Yao Lai,Xiao Zhang,Juan An,Jin-Xiu Li,Li Li,Liang Wu,Yi-Ting Lin,Dong-Ye Wang,Jiang-Shan Xu,Shi-Jie Hao,Yang Wang,Rong-Hai Li,Wen Ma,Yu-Mo Song,Chang Liu,Chuan-Yu Liu,Zhen Dai,Yan Xu,Amar Deep Sharma,Michael Ott,Qing Ou-Yang,Feng Huo,Rong Fan,Yong-Yin Li,Jin-Lin Hou,Giacomo Volpe,Long-Qi Liu,Miguel A.Esteban,Yi-Wei Lai..Cell atlas of CCl_(4)-induced progressive liver fibrosis reveals stage-specific responses[J].动物学研究(英文),2023,44(3):P.451-466,16.基金项目
supported by the National Natural Science Foundation of China(32200688,92068106,U20A2015,32211530050) （32200688,92068106,U20A2015,32211530050）
Guangdong Basic and Applied Basic Research Foundation(2021B1515120075,2021A1515110180) （2021B1515120075,2021A1515110180）
Science and Technology Program of Guangzhou(202201010408,202201011037)。 （202201010408,202201011037）
