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首页|期刊导航|农业科学学报(英文)|Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

XU Kui LI Kui ZHOU Yan-rong SHANG Hai-tao XU Chang-jiang TAO Ran HAO Wan-jun LIU Sha-sha MU Yu-lian XIAO Shao-bo

农业科学学报(英文)2023,Vol.22Issue(7):2188-2199,12.
农业科学学报(英文)2023,Vol.22Issue(7):2188-2199,12.DOI:10.1016/j.jia.2022.11.010

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

XU Kui 1LI Kui 2ZHOU Yan-rong 3SHANG Hai-tao 4XU Chang-jiang 2TAO Ran 3HAO Wan-jun 3LIU Sha-sha 2MU Yu-lian 2XIAO Shao-bo3

作者信息

  • 1. State Key Laboratory of Animal Nutrition/Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture and Rural Affairs,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,P.R.China||Shenzhen Kingsino Technology Co.,Ltd.,Shenzhen 518106,P.R.China
  • 2. State Key Laboratory of Animal Nutrition/Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture and Rural Affairs,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,P.R.China
  • 3. State Key Laboratory of Agricultural Microbiology/Key Laboratory of Preventive Veterinary Medicine in Hubei Province,College of Veterinary Medicine,Huazhong Agricultural University,Wuhan 430070,P.R.China
  • 4. Shenzhen Kingsino Technology Co.,Ltd.,Shenzhen 518106,P.R.China||Precision Medicine Institute,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,P.R.China
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摘要

关键词

pigs/porcine alveolar macrophages/dual-sgRNA/homology-directed repair/PRRSV/CD163

Key words

pigs/porcine alveolar macrophages/dual-sgRNA/homology-directed repair/PRRSV/CD163

引用本文复制引用

XU Kui,LI Kui,ZHOU Yan-rong,SHANG Hai-tao,XU Chang-jiang,TAO Ran,HAO Wan-jun,LIU Sha-sha,MU Yu-lian,XIAO Shao-bo..Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus[J].农业科学学报(英文),2023,22(7):2188-2199,12.

基金项目

This work was supported by the Major Scientific Research Tasks for Scientific and Technological Innovation Projects of the Chinese Academy of Agricultural Sciences(CAAS-ZDRW202006),the National Transgenic Breeding Project,China(2018ZX08009-26B),the Shenzhen Science and Technology Plan Project,China(CJGJZD20210408092402006),and the Shenzhen Key Technology Projects,China(JSGG20180507182028625). (CAAS-ZDRW202006)

农业科学学报(英文)

OACSCDCSTPCD

2095-3119

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