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Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

Jiuping Zeng Jing Shen Fukuan Du Yu Chen Shuai Deng Fang Wang Zhuo Zhang Zhi Li Tiangang Wang Shengpeng Wang Zhangang Xiao Mingxing Li Xu Wu Qianyun Zhao Meijuan Chen Long Zhao Shulin Wei Huan Yang Yueshui Zhao Anqi Wang

药物分析学报(英文)2023,Vol.13Issue(6):545-562,18.
药物分析学报(英文)2023,Vol.13Issue(6):545-562,18.DOI:10.1016/j.jpha.2023.05.009

Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

Jiuping Zeng 1Jing Shen 2Fukuan Du 2Yu Chen 2Shuai Deng 2Fang Wang 1Zhuo Zhang 1Zhi Li 3Tiangang Wang 3Shengpeng Wang 4Zhangang Xiao 5Mingxing Li 2Xu Wu 6Qianyun Zhao 1Meijuan Chen 7Long Zhao 3Shulin Wei 1Huan Yang 1Yueshui Zhao 2Anqi Wang8

作者信息

  • 1. Laboratory of Molecular Pharmacology,Department of Pharmacology,School of Pharmacy,Southwest Medical University,Luzhou,Sichuan,646000,China||Cell Therapy & Cell Drugs of Luzhou Key Laboratory,Luzhou,Sichuan,646000,China
  • 2. Laboratory of Molecular Pharmacology,Department of Pharmacology,School of Pharmacy,Southwest Medical University,Luzhou,Sichuan,646000,China||Cell Therapy & Cell Drugs of Luzhou Key Laboratory,Luzhou,Sichuan,646000,China||South Sichuan Institute of Translational Medicine,Luzhou,Sichuan,646000,China
  • 3. Department of Spleen and Stomach Diseases,The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Luzhou,Sichuan,646000,China
  • 4. State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Macao,999078,China
  • 5. Laboratory of Molecular Pharmacology,Department of Pharmacology,School of Pharmacy,Southwest Medical University,Luzhou,Sichuan,646000,China||Department of Oncology,The Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan,646000,China
  • 6. Laboratory of Molecular Pharmacology,Department of Pharmacology,School of Pharmacy,Southwest Medical University,Luzhou,Sichuan,646000,China||State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Macao,999078,China
  • 7. Laboratory of Molecular Pharmacology,Department of Pharmacology,School of Pharmacy,Southwest Medical University,Luzhou,Sichuan,646000,China
  • 8. School of Medicine,Chengdu University,Chengdu,610106,China
  • 折叠

摘要

关键词

T helper 17/RORγt/Small-molecule inhibitor/Inflammatory disease/Autoimmune disease

Key words

T helper 17/RORγt/Small-molecule inhibitor/Inflammatory disease/Autoimmune disease

引用本文复制引用

Jiuping Zeng,Jing Shen,Fukuan Du,Yu Chen,Shuai Deng,Fang Wang,Zhuo Zhang,Zhi Li,Tiangang Wang,Shengpeng Wang,Zhangang Xiao,Mingxing Li,Xu Wu,Qianyun Zhao,Meijuan Chen,Long Zhao,Shulin Wei,Huan Yang,Yueshui Zhao,Anqi Wang..Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases[J].药物分析学报(英文),2023,13(6):545-562,18.

基金项目

This work was supported by the grants from the Sichuan Science and Technology Program,China(Grant Nos.:2023NSFSC0614 and 2022YFS0624),Southwest Medical University Science and Tech-nology Program,China(Grant No.:2021ZKZD017),the Luzhou Science and Technology Program,China(Grant Nos.:2022-YJY-127,2022YFS0624-B1,2022YFS0624-C1,and 2022YFS0624-B3),and the Open Research Project Program funded by the Science and Tech-nology Development Fund(Grant No.:SKL-QRCM(UM)-2020-2022)and the State Key Laboratory of Quality Research in Chinese Med-icine(University of Macau,Macao,China)(Grant No.:SKL-QRCM-OP21006). (Grant Nos.:2023NSFSC0614 and 2022YFS0624)

药物分析学报(英文)

OACSCD

2095-1779

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