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Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer

Han Xiao Rong Zhao Wangyang Meng Yongde Liao

药物分析学报(英文)2023,Vol.13Issue(6):625-639,15.
药物分析学报(英文)2023,Vol.13Issue(6):625-639,15.DOI:10.1016/j.jpha.2023.04.009

Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer

Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer

Han Xiao 1Rong Zhao 1Wangyang Meng 2Yongde Liao1

作者信息

  • 1. Department of Thoracic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430022,China
  • 2. Department of Thoracic Surgery,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200025,China
  • 折叠

摘要

关键词

STM2457/METTL3/Translatomics/Non-small cell lung cancer/PD-L1

Key words

STM2457/METTL3/Translatomics/Non-small cell lung cancer/PD-L1

引用本文复制引用

Han Xiao,Rong Zhao,Wangyang Meng,Yongde Liao..Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer[J].药物分析学报(英文),2023,13(6):625-639,15.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant No.:82072593).We would like to thank the research team of Dr.Eliza Yankova,who initially synthesized STM2457 and published its structure.We are also grateful to Dr.Junho Choe and his research team for their pioneering work in the field of METTL3-mediated translation regulation. (Grant No.:82072593)

药物分析学报(英文)

OACSCD

2095-1779

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