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Identification,structure elucidation and origin of a common pyridinium-thiocyanate intermediate in electrospray mass spectrometry among the benziamidazole-class proton pump inhibitors

Dong Sun Chunyu Wang Yanxia Fan Jingkai Gu

药物分析学报(英文)2023,Vol.13Issue(6):683-688,6.
药物分析学报(英文)2023,Vol.13Issue(6):683-688,6.DOI:10.1016/j.jpha.2023.04.011

Identification,structure elucidation and origin of a common pyridinium-thiocyanate intermediate in electrospray mass spectrometry among the benziamidazole-class proton pump inhibitors

Identification,structure elucidation and origin of a common pyridinium-thiocyanate intermediate in electrospray mass spectrometry among the benziamidazole-class proton pump inhibitors

Dong Sun 1Chunyu Wang 2Yanxia Fan 3Jingkai Gu4

作者信息

  • 1. Research Center for Drug Metabolism,School of Life Sciences,Jilin University,Changchun,130012,China
  • 2. State Key Laboratory of Supramolecular Structure and Materials,Jilin University,Changchun,130012,China
  • 3. Jilin Institute for Drug Control,Changchun,130033,China
  • 4. Research Center for Drug Metabolism,School of Life Sciences,Jilin University,Changchun,130012,China||State Key Laboratory of Supramolecular Structure and Materials,Jilin University,Changchun,130012,China||Beijing Institute of Drug Metabolism,Beijing,102209,China
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摘要

关键词

Proton pump inhibitor/Mass spectrometry/Electrospray ionization/Pseudo-molecular ion/Pyridinium thiocyanate

Key words

Proton pump inhibitor/Mass spectrometry/Electrospray ionization/Pseudo-molecular ion/Pyridinium thiocyanate

引用本文复制引用

Dong Sun,Chunyu Wang,Yanxia Fan,Jingkai Gu..Identification,structure elucidation and origin of a common pyridinium-thiocyanate intermediate in electrospray mass spectrometry among the benziamidazole-class proton pump inhibitors[J].药物分析学报(英文),2023,13(6):683-688,6.

基金项目

This study is supported by the National Natural Science Foun-dation of China(Grant Nos.:82030107 and 81872831)and the National Science and Technology Major Projects for significant new drugs creation of the 13th five-year plan(Grant Nos.:2017ZX09101001 and 2018ZX09721002007). (Grant Nos.:82030107 and 81872831)

药物分析学报(英文)

OACSCD

2095-1779

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