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PAI-1 genetic polymorphisms influence septic patients'outcomes by regulating neutrophil activity

Shaowei Jiang Shuming Pan Chengjin Gao Yang Wang Liang Chen Honghua Mu Connor Meaney Yiwen Fan Janesh Pillay Hairong Wang Jincheng Zhang

中华医学杂志（英文版）2023，Vol.136Issue(16)：1959-1966,8.

中华医学杂志（英文版）2023，Vol.136Issue(16)：1959-1966,8.DOI:10.1097/CM9.0000000000002316

PAI-1 genetic polymorphisms influence septic patients'outcomes by regulating neutrophil activity

Shaowei Jiang ¹Shuming Pan ¹Chengjin Gao ¹Yang Wang ¹Liang Chen ¹Honghua Mu ²Connor Meaney ²Yiwen Fan ³Janesh Pillay ⁴Hairong Wang ¹Jincheng Zhang⁵

作者信息

1. Department of Emergency,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China
2. Division of Rheumatology,Department of Internal Medicine,University of Utah School of Medicine,Salt Lake City,UT,USA
3. Department of Pathology Medicine Biology,University Medical Center Groningen,The Netherlands
4. Department of Critical Care,University Medical Center Groningen,The Netherlands
5. Department of Critical Care Medicine,Zhongshan Hospital,Fudan University,Shanghai 200032,China
折叠

摘要

关键词

Gene polymorphism/Neutrophil/Plasminogen activator inhibitor-1/PAI-1/Sepsis/Single nucleotide polymorphism

Key words

Gene polymorphism/Neutrophil/Plasminogen activator inhibitor-1/PAI-1/Sepsis/Single nucleotide polymorphism

引用本文复制引用

Shaowei Jiang,Shuming Pan,Chengjin Gao,Yang Wang,Liang Chen,Honghua Mu,Connor Meaney,Yiwen Fan,Janesh Pillay,Hairong Wang,Jincheng Zhang..PAI-1 genetic polymorphisms influence septic patients'outcomes by regulating neutrophil activity[J].中华医学杂志（英文版）,2023,136(16):1959-1966,8.

基金项目

This work was supported by grants from the National Natural Science Foundation of China(Nos.82172138 and 81873947),Special Medical Innovation Project of Shanghai Science and Technology Committee(No.21Y11902400),and the Key Laboratory of Emergency and Trauma(Hainan Medical University),Ministry of Education(No.KLET-202016). （Nos.82172138 and 81873947）

中华医学杂志（英文版）

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