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Identification and epitope mapping of anti-p72 single-chain antibody against African swine fever virus based on phage display antibody library

SONG Jin-xing WU Ya-nan ZHANG Gai-ping WANG Meng-xiang ZHANG Yi-xuan WAN Bo DU Yong-kun ZHUANG Guo-qing LI Zi-bin QIAO Song-lin GENG Rui

农业科学学报（英文）2023，Vol.22Issue(9)：2834-2847,14.

农业科学学报（英文）2023，Vol.22Issue(9)：2834-2847,14.DOI:10.1016/j.jia.2023.07.039

Identification and epitope mapping of anti-p72 single-chain antibody against African swine fever virus based on phage display antibody library

SONG Jin-xing ¹WU Ya-nan ¹ZHANG Gai-ping ²WANG Meng-xiang ¹ZHANG Yi-xuan ¹WAN Bo ¹DU Yong-kun ¹ZHUANG Guo-qing ¹LI Zi-bin ³QIAO Song-lin ⁴GENG Rui⁵

作者信息

1. College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450046,P.R.China||International Joint Research Center of National Animal Immunology,Zhengzhou 450046,P.R.China
2. College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450046,P.R.China||International Joint Research Center of National Animal Immunology,Zhengzhou 450046,P.R.China||Longhu Laboratory,Zhengzhou 450046,P.R.China||School of Advanced Agricultural Sciences,Peking University,Beijing 100871,P.R.China
3. College of Animal Science and Veterinary Medicine,Tianjin Agricultural University,Tianjin 300384,P.R.China
4. Henan Provincial Key Laboratory of Animal Immunology,Henan Academy of Agricultural Sciences,Zhengzhou 450002,P.R.China
5. College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450046,P.R.China
折叠

摘要

关键词

ASFV/phage display antibody library/single chain antibody(scFv)/p72/epitope

Key words

ASFV/phage display antibody library/single chain antibody(scFv)/p72/epitope

引用本文复制引用

SONG Jin-xing,WU Ya-nan,ZHANG Gai-ping,WANG Meng-xiang,ZHANG Yi-xuan,WAN Bo,DU Yong-kun,ZHUANG Guo-qing,LI Zi-bin,QIAO Song-lin,GENG Rui..Identification and epitope mapping of anti-p72 single-chain antibody against African swine fever virus based on phage display antibody library[J].农业科学学报（英文）,2023,22(9):2834-2847,14.

基金项目

This work was supported by the National Natural Science Foundation of China(31941001 and 32002292),the Major Science and Technology Project of Henan Province,China(221100110600)and the Natural Science Foundation of Henan Province(202300410199).Sample of inactivated porcine alveolar macrophage(PAM)cells infected with ASFV Pig/HLJ/18 strain was kindly provided by Prof.Li Huang in Harbin Veterinary Research Institute,CAAS. （31941001 and 32002292）

农业科学学报（英文）

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ISSN：2095-3119

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