首页|期刊导航|国际口腔科学杂志（英文版）|Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation

Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation

Jue Wang Abigail McVicar Yilin Chen Hong-Wen Deng Zhihe Zhao Wei Chen Yi-Ping Li

国际口腔科学杂志（英文版）2023，Vol.15Issue(3)：390-400,11.

国际口腔科学杂志（英文版）2023，Vol.15Issue(3)：390-400,11.DOI:10.1038/s41368-023-00235-2

Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation

Jue Wang ¹Abigail McVicar ²Yilin Chen ²Hong-Wen Deng ³Zhihe Zhao ⁴Wei Chen ⁵Yi-Ping Li⁵

作者信息

1. Department of Pathology,School of Medicine,University of Alabama at Birmingham,Birmingham,AL,USA||State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
2. Division in Cellular and Molecular Medicine,Department of Pathology and Laboratory Medicine,Tulane University School of Medicine,Tulane University,New Orleans,LA,USA
3. Tulane Center of Biomedical Informatics and Genomics,Deming Department of Medicine,Tulane University School of Medicine,New Orleans,LA,USA
4. State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
5. Department of Pathology,School of Medicine,University of Alabama at Birmingham,Birmingham,AL,USA||Division in Cellular and Molecular Medicine,Department of Pathology and Laboratory Medicine,Tulane University School of Medicine,Tulane University,New Orleans,LA,USA
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Jue Wang,Abigail McVicar,Yilin Chen,Hong-Wen Deng,Zhihe Zhao,Wei Chen,Yi-Ping Li..Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation[J].国际口腔科学杂志（英文版）,2023,15(3):390-400,11.

基金项目

We thank Dr.Hongbing Jiang and Dr.Yan Zhang for their excellent assistance in tooth root phenotype analysis in ATP6i deficient mice.We thank Dr.Joel Jules for critical reading of the manuscript,and Dr.Anne Poliard for providing A4 pulp precursor cell line.This work was supported by the National Institutes of Health[DE023813 and DE028264 to Y.P.L.,and AG056438 and AR070135 to W.C.],and the UAB National Institutes of Health National Institute of Dental and Craniofacial Research[Dental Academic Research Training Grant(DART)5T90DE022736 to J.W.].The authors declare no potential conflicts of interest with respect to the authorship and/or publication of this article. （DART）

国际口腔科学杂志（英文版）

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ISSN：1674-2818

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