Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis
Jiayun Chen Xueling He Yunmeng Bai Jing Liu Yin Kwan Wong Lulin Xie Qian Zhang Piao Luo Peng Gao Liwei Gu Qiuyan Guo Guangqing Cheng Chen Wang Jigang Wang
Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis
摘要
关键词
Artesunate/Sepsis/Single-cell RNA sequencing/Immunomodulatory activity分类
医药卫生引用本文复制引用
Jiayun Chen,Xueling He,Yunmeng Bai,Jing Liu,Yin Kwan Wong,Lulin Xie,Qian Zhang,Piao Luo,Peng Gao,Liwei Gu,Qiuyan Guo,Guangqing Cheng,Chen Wang,Jigang Wang..Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis[J].药物分析学报:英文版,2023,13(7):P.817-829,13.基金项目
support by the Establishment of Sino-Austria“Belt and Road”Joint Laboratory on Traditional Chinese Medicine for Severe Infectious Diseases and Joint Research,China(Grant No.:2020YFE0205100) （Grant No.:2020YFE0205100）
the National Key Research and Development Program of China(Grant Nos.:2020YFA0908000,2022YFC2303600) （Grant Nos.:2020YFA0908000,2022YFC2303600）
the Distinguished Expert Project of Sichuan Province Tianfu Scholar(Grant No.:CW202002) （Grant No.:CW202002）
the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine,China(Grant No.:ZYYCXTD-C-202002) （Grant No.:ZYYCXTD-C-202002）
the National Natural Science Foundation of China(Grant Nos.:82141001,82274182,82074098,82173914) （Grant Nos.:82141001,82274182,82074098,82173914）
the China Academy of Chinese Medical Sciences(CACMS)Innovation Fund,China(Grant Nos.:CI2021A05101,CI2021A05104) （CACMS）
the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(Grant No.:CI2021B014) （Grant No.:CI2021B014）
the Science and Technology Foundation of Shenzhen,China(Grant No.:JCYJ20210324115800001) （Grant No.:JCYJ20210324115800001）
the Science and Technology Foundation of Shenzhen,China(Shenzhen Clinical Medical Research Center for Geriatric Diseases),the National Key R&D Program of China Key Projects for International Cooperation on Science,Technology and Innovation(Grant No.:2020YFE0205100) （Shenzhen Clinical Medical Research Center for Geriatric Diseases）
the Fundamental Research Funds for the Central Public Welfare Research Institutes,China(Grant Nos.:ZZ14-YQ-050,ZZ14-YQ-051,ZZ14-YQ-052,ZZ14-FL-002,ZZ14-ND-010,ZZ15-ND-10),Shenzhen Governmental Sustainable Development Fund,China(Grant No.:KCXFZ20201221173612034) （Grant Nos.:ZZ14-YQ-050,ZZ14-YQ-051,ZZ14-YQ-052,ZZ14-FL-002,ZZ14-ND-010,ZZ15-ND-10）
Shenzhen key Laboratory of Kidney Diseases,China(Grant No.:ZDSYS201504301616234) （Grant No.:ZDSYS201504301616234）
Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties,China(Grant No.:SZGSP001). （Grant No.:SZGSP001）
