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首页|期刊导航|药物分析学报:英文版|Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

Lingqi Yu Jun Yan Yingqi Zhan Anyao Li Lidan Zhu Jingyang Qian Fanfan Zhou Xiaoyan Lu Xiaohui Fan

药物分析学报:英文版2023,Vol.13Issue(8):P.926-941,16.
药物分析学报:英文版2023,Vol.13Issue(8):P.926-941,16.DOI:10.1016/j.jpha.2023.05.004

Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

Lingqi Yu 1Jun Yan 2Yingqi Zhan 2Anyao Li 1Lidan Zhu 2Jingyang Qian 1Fanfan Zhou 3Xiaoyan Lu 4Xiaohui Fan5

作者信息

  • 1. Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China Future Health Laboratory,Innovation Center of Yangtze River Delta,Zhejiang University,Jiaxing,Zhejiang,314100,China
  • 2. Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China
  • 3. School of Pharmacy,The University of Sydney,Sydney,2006,Australia
  • 4. Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China Future Health Laboratory,Innovation Center of Yangtze River Delta,Zhejiang University,Jiaxing,Zhejiang,314100,China Innovation Center in Zhejiang University,State Key Laboratory of Component-Based Chinese Medicine,Hangzhou 310058,China Jinhua Institute of Zhejiang University,Jinhua,Zhejiang,321016,China Hangzhou Institute of Innovative Medicine,Zhejiang University,Hangzhou,310058,China
  • 5. Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China Future Health Laboratory,Innovation Center of Yangtze River Delta,Zhejiang University,Jiaxing,Zhejiang,314100,China Innovation Center in Zhejiang University,State Key Laboratory of Component-Based Chinese Medicine,Hangzhou 310058,China Jinhua Institute of Zhejiang University,Jinhua,Zhejiang,321016,China Engineering Research Center of Innovative Anticancer Drugs,Ministry of Education,Harbin,150023,China
  • 折叠

摘要

关键词

Single-cell RNA sequencing/Drug-induced liver injury/Autoprotection against APAP hepatotoxicity/Endothelial cells/Dendritic cells

分类

医药卫生

引用本文复制引用

Lingqi Yu,Jun Yan,Yingqi Zhan,Anyao Li,Lidan Zhu,Jingyang Qian,Fanfan Zhou,Xiaoyan Lu,Xiaohui Fan..Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity[J].药物分析学报:英文版,2023,13(8):P.926-941,16.

基金项目

supported by the National Natural Science Foundation of China(Grant No.:81870426) (Grant No.:81870426)

the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Grant No.:ZYYCXTD-D-202002) (Grant No.:ZYYCXTD-D-202002)

the Fundamental Research Funds for the Central Universities(Grant No.:226-2023-00059),and the Fundamental Research Funds for the Central Universities. (Grant No.:226-2023-00059)

药物分析学报:英文版

OACSCD

2095-1779

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