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A single-cell landscape of triptolide-associated testicular toxicity in mice

Wei Zhang Siyu Xia Jinhuan Ou Min Cao Guangqing Cheng Zhijie Li Jigang Wang Chuanbin Yang

药物分析学报:英文版2023，Vol.13Issue(8)：P.880-893,14.

药物分析学报:英文版2023，Vol.13Issue(8)：P.880-893,14.DOI:10.1016/j.jpha.2023.04.006

A single-cell landscape of triptolide-associated testicular toxicity in mice

Wei Zhang ¹Siyu Xia ¹Jinhuan Ou ¹Min Cao ¹Guangqing Cheng ²Zhijie Li ¹Jigang Wang ³Chuanbin Yang¹

作者信息

1. Department of Nephrology,Shenzhen Key Laboratory of Kidney Diseases,Shenzhen Clinical Research Centre for Geriatrics,Shenzhen People''s Hospital(The Second Clinical Medical College,Jinan University,The First Affiliated Hospital,Southern University of Science and Technology),Shenzhen,Guangdong,518020,China
2. State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,Artemisinin Research Center,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,10700,China
3. Department of Nephrology,Shenzhen Key Laboratory of Kidney Diseases,Shenzhen Clinical Research Centre for Geriatrics,Shenzhen People''s Hospital(The Second Clinical Medical College,Jinan University,The First Affiliated Hospital,Southern University of Science and Technology),Shenzhen,Guangdong,518020,China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,Artemisinin Research Center,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,10700,China
折叠

摘要

关键词

Single-cell sequence/Transcriptomics/Triptolide/Reproduction toxicity/Testis

分类

医药卫生

引用本文复制引用

Wei Zhang,Siyu Xia,Jinhuan Ou,Min Cao,Guangqing Cheng,Zhijie Li,Jigang Wang,Chuanbin Yang..A single-cell landscape of triptolide-associated testicular toxicity in mice[J].药物分析学报:英文版,2023,13(8):P.880-893,14.

基金项目

supported by grants from the National Key Research and Development Program of China(Grant Nos.:2020YFA0908000,2022YFC2303600) （Grant Nos.:2020YFA0908000,2022YFC2303600）

the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Grant No.:ZYYCXTD-C-202002) （Grant No.:ZYYCXTD-C-202002）

the National Natural Science Foundation of China(Grant Nos.:82201786,82141001,82274182,82074098,82173914) （Grant Nos.:82201786,82141001,82274182,82074098,82173914）

the CACMS Innovation Fund(Grant Nos.:CI2021A05101,CI2021A05104) （Grant Nos.:CI2021A05101,CI2021A05104）

the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(Grant No.:CI2021B014) （Grant No.:CI2021B014）

the Science and Technology Foundation of Shenzhen(Grant Nos.:JCYJ20220818102613029,JCYJ20210324114014039,JCYJ20210324115800001) （Grant Nos.:JCYJ20220818102613029,JCYJ20210324114014039,JCYJ20210324115800001）

Guangdong Basic and Applied Basic Research Foundation(Grant Nos.:2020A1515110549,2021A1515110646) （Grant Nos.:2020A1515110549,2021A1515110646）

the Science and Technology Foundation of Shenzhen(Shenzhen Clinical Medical Research Center for Geriatric Diseases) （Shenzhen Clinical Medical Research Center for Geriatric Diseases）

the National Key R&D Program of China Key projects for international cooperation on science,technology and innovation(Grant No.:2020YFE0205100) （Grant No.:2020YFE0205100）

and the Fundamental Research Funds for the Central Public Welfare Research Institutes(Grant Nos.:ZZ14-YQ-050,ZZ14-YQ-051,ZZ14-YQ-052,ZZ14-FL-002,ZZ14-ND-010,ZZ15-ND-10). （Grant Nos.:ZZ14-YQ-050,ZZ14-YQ-051,ZZ14-YQ-052,ZZ14-FL-002,ZZ14-ND-010,ZZ15-ND-10）

药物分析学报:英文版

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ISSN：2095-1779

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