数字中医药（英文）2023，Vol.6Issue(3)：357-368,12.DOI:10.1016/j.dcmed.2023.10.010
基于文献计量学的药食同源健脾类保健食品专利的研究趋势与发展前景分析:2000-2022年
Patents research and development prospects of spleen-invigorating health food with the homology of medicine and food from 2000 to 2022:a bibliometric analysis
摘要
Abstract
Objective To analyze the current status and development trends of the patents of spleen-in-vigorating health food with the homology of medicine and food in China,and to provide ideas and references for the research and development of traditional Chinese medicine(TCM)spleen-invigorating health food with the homology of medicine and food. Methods The State Administration for Market Regulation website's"Special Food Informa-tion Query Platform"and the incoPat global patent database were searched in this study.Based on the methods of bibliometrics,the registered health food and patents related to spleen-invigorating health food with the homology of medicine and food in China were sort-ed out.Furthermore,the research and development numbers,provinces,institutions,tech-nology and efficacy classification,major drugs,active ingredients and others of invigorating spleen health food in China were analyzed,and filtered patent data were visualized and ana-lyzed by R programming language and CytoScape software. Results A total of 285 patents of health food with the homology of medicine and food for in-vigorating spleen were included and analyzed.From 2012,the patent registration numbers of these spleen-invigorating health food with the homology of medicine and food increased sig-nificantly in China.Over the past 20 years,the top five provinces in terms of patent disclo-sures were Guangdong,Anhui,Jiangsu,Shandong,and Guangxi.It was found that the techni-cal efficacy of over 20 patents was described as"immune enhancement""digestion""disease prevention",etc.Patent applications were mainly aimed at the research and development of the preservation of food or ingredients,the specific therapeutic activity of compounds,and pharmaceutical preparations,which were led by corporation research and development registrations,and supplemented by applications from research institutions and individuals.Among the 285 patents,the top 10 raw materials of spleen-invigorating health food with the homology of medicine and food were Shanyao(Dioscoreae Rhizoma),Fuling(Poria),Shanzha(Crataegi Fructus),Baizhu(Atractylodis Macrocephalae Rhizoma),Chenpi(Citri Reticulatae Pericarpium),Dazao(Jujubae Fructus),Gancao(Glycyrrhizae Radix et Rhizoma),Fengmi(Mel),Maiya(Hordei Fructus Germinatus),and Dangshen(Salviae Miltiorrhizae Radix et Rhizoma).The main functions were to nourish spleen and replenish Qi,invigorate spleen and benefit lungs,nourish blood and promote fluid production,and nourish spleen and stomach. Conclusion The main drug composition and functional components of spleen-invigorating health food with the homology of medicine and food are relatively clear,and the technical ef-fects of invigorating the spleen and stomach,eliminating accumulation of food,and enhanc-ing immunity are highly targeted.This paper provides evidence for the research and develop-ment,mechanism research,and process improvement of spleen-invigorating health food with the homology of medicine and food in the future.关键词
中医药/药食同源/健脾/保健食品/专利/文献计量学/可视化分析Key words
Traditional Chinese medicine(TCM)/Medicine and food homologous/Invigorating spleen/Health food/Patents/Bibliometric analysis/Visual analysis引用本文复制引用
刘萍,方锐,何佳维,李泽,周月,杨勇,成绍武..基于文献计量学的药食同源健脾类保健食品专利的研究趋势与发展前景分析:2000-2022年[J].数字中医药（英文）,2023,6(3):357-368,12.基金项目
The Natural Science Foundation of Hunan Province(2022JJ50048). （2022JJ50048）
