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首页|期刊导航|中华医学杂志（英文版）|Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores:evidence from the China Kadoorie Biobank

Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores:evidence from the China Kadoorie Biobank

Songchun Yang Ling Yang Iona Y.Millwood Robin G.Walters Yiping Chen Huaidong Du Zengchang Pang Dan Schmidt Rebecca Stevens Robert Clarke Junshi Chen Dong Sun Zhengming Chen Jun Lv Liming Li Zhijia Sun Canqing Yu Yu Guo Jiahui Si Dianjianyi Sun Yuanjie Pang Pei Pei

中华医学杂志（英文版）2023，Vol.136Issue(20)：2476-2483,8.
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中华医学杂志（英文版）2023，Vol.136Issue(20)：2476-2483,8.DOI:10.1097/CM9.0000000000002694

Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores:evidence from the China Kadoorie Biobank

Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores:evidence from the China Kadoorie Biobank

Songchun Yang 1Ling Yang 2Iona Y.Millwood 2Robin G.Walters 2Yiping Chen 2Huaidong Du 2Zengchang Pang 3Dan Schmidt 4Rebecca Stevens 4Robert Clarke 4Junshi Chen 5Dong Sun 6Zhengming Chen 4Jun Lv 7Liming Li 7Zhijia Sun 6Canqing Yu 7Yu Guo 8Jiahui Si 6Dianjianyi Sun 7Yuanjie Pang 6Pei Pei9

作者信息

  • 2. Medical Research Council Population Health Research Unit at the University of Oxford,Oxford OX3 7LF,UK||Clinical Trial Service Unit and Epidemiological Studies Unit(CTSU),Nuffield Department of Population Health,University of Oxford,Oxford OX3 7LF,UK
  • 3. Qingdao Center of Disease Control and Prevention,Qingdao,Shandong 266033,China
  • 4. Clinical Trial Service Unit and Epidemiological Studies Unit(CTSU),Nuffield Department of Population Health,University of Oxford,Oxford OX3 7LF,UK
  • 5. China National Center for Food Safety Risk Assessment,Beijing 100738,China
  • 6. Department of Epidemiology and Biostatistics,School of Public Health,Peking University,Beijing 100191,China
  • 7. Department of Epidemiology and Biostatistics,School of Public Health,Peking University,Beijing 100191,China||Peking University Center for Public Health and Epidemic Preparedness & Response,Beijing 100191,China
  • 8. FuwaiHospital Chinese Academy of Medical Sciences,Beijing 100730,China
  • 9. Peking University Center for Public Health and Epidemic Preparedness & Response,Beijing 100191,China
  • 折叠

摘要

关键词

Coronary artery disease/Polygenic risk score/Risk prediction model/Chinese population

Key words

Coronary artery disease/Polygenic risk score/Risk prediction model/Chinese population

引用本文复制引用

Songchun Yang,Ling Yang,Iona Y.Millwood,Robin G.Walters,Yiping Chen,Huaidong Du,Zengchang Pang,Dan Schmidt,Rebecca Stevens,Robert Clarke,Junshi Chen,Dong Sun,Zhengming Chen,Jun Lv,Liming Li,Zhijia Sun,Canqing Yu,Yu Guo,Jiahui Si,Dianjianyi Sun,Yuanjie Pang,Pei Pei..Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores:evidence from the China Kadoorie Biobank[J].中华医学杂志（英文版）,2023,136(20):2476-2483,8.

基金项目

This work was supported by grants from the National Natural Science Foundation of China(Nos.82192904,82192901,82192900,and 91846303).The CKB baseline survey and the first re-survey were supported by a grant from the Kadoorie Charitable Foundation in Hong Kong.The long-term follow-up is supported by grants from the UK Wellcome Trust(Nos.212946/Z/18/Z,202922/Z/16/Z,104085/Z/14/Z,and 088158/Z/09/Z),the National Key Research and Development Program of China(No.2016 YFC0900500),National Natural Science Foundation of China(No.81390540),and Chinese Ministry of Science and Technology(No.2011BAI09B01). （Nos.82192904,82192901,82192900,and 91846303）

中华医学杂志（英文版）

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