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Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy

Hailong He Annette Ziegler Vasilis Ntziachristos Nikolina-Alexia Fasoula Angelos Karlas Murad Omar Juan Aguirre Jessica Lutz Michael Kallmayer Martin Füchtenbusch Hans-Henning Eckstein

光：科学与应用（英文版）2023，Vol.12Issue(11)：2335-2349,15.

光：科学与应用（英文版）2023，Vol.12Issue(11)：2335-2349,15.DOI:10.1038/s41377-023-01275-3

Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy

Hailong He ¹Annette Ziegler ²Vasilis Ntziachristos ³Nikolina-Alexia Fasoula ¹Angelos Karlas ⁴Murad Omar ¹Juan Aguirre ¹Jessica Lutz ⁵Michael Kallmayer ⁶Martin Füchtenbusch ⁵Hans-Henning Eckstein⁷

作者信息

1. Institute of Biological and Medical Imaging,Helmholtz Zentrum München,Neuherberg,Germany||Chair of Biological Imaging at the Central Institute for Translational Cancer Research(TranslaTUM),School of Medicine,Technical University of Munich,Munich,Germany
2. Forschergruppe Diabetes e.V.,Helmholtz Zentrum München,Neuherberg,Germany||institute of Diabetes Research,Helmholtz Zentrum München,Neuherberg,Germany
3. Institute of Biological and Medical Imaging,Helmholtz Zentrum München,Neuherberg,Germany||Chair of Biological Imaging at the Central Institute for Translational Cancer Research(TranslaTUM),School of Medicine,Technical University of Munich,Munich,Germany||DZHK(German Centre for Cardiovascular Research),partner site Munich Heart Alliance,Munich,Germany
4. Institute of Biological and Medical Imaging,Helmholtz Zentrum München,Neuherberg,Germany||Chair of Biological Imaging at the Central Institute for Translational Cancer Research(TranslaTUM),School of Medicine,Technical University of Munich,Munich,Germany||Department for Vascular and Endovascular Surgery,Klinikum rechts der Isar,Technical University of Munich(TUM),Munich,Germany||DZHK(German Centre for Cardiovascular Research),partner site Munich Heart Alliance,Munich,Germany
5. Diabetes Center at Marienplatz,Munich,Germany||Forschergruppe Diabetes e.V.,Helmholtz Zentrum München,Neuherberg,Germany
6. Department for Vascular and Endovascular Surgery,Klinikum rechts der Isar,Technical University of Munich(TUM),Munich,Germany
7. Department for Vascular and Endovascular Surgery,Klinikum rechts der Isar,Technical University of Munich(TUM),Munich,Germany||DZHK(German Centre for Cardiovascular Research),partner site Munich Heart Alliance,Munich,Germany
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Hailong He,Annette Ziegler,Vasilis Ntziachristos,Nikolina-Alexia Fasoula,Angelos Karlas,Murad Omar,Juan Aguirre,Jessica Lutz,Michael Kallmayer,Martin Füchtenbusch,Hans-Henning Eckstein..Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy[J].光：科学与应用（英文版）,2023,12(11):2335-2349,15.

基金项目

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 687866(INNODERM)and No 871763(WINTHER),from the European Research Council(ERC)under the European Union's Horizon 2020 research and innovation programme under grant agreement No 694968(PREMSOT)and from Helmholtz Zentrum München through Physician Scientists for Groundbreaking Projects,in part by the Helmholtz Association of German Research Center,through the Initiative and Networking Fund,i3(ExNet-0022-Phase2-3),and from the DZHK(German Centre for Cardiovascular Research （INNODERM）

FKZ 81Z0600104).We thank Dr.Robert J.Wilson and Dr Serene Lee for their attentive reading and improvements of the manuscript.We express our gratitude to the staff at the Diabetes Center in Marienplatz,Munich,Germany as well as the Department for Vascular and Endovascular Surgery,Klinikum rechts der Isar,Technical University of Munich(TUM),Germany,for their valuable assistance in conducting the study presented here.Open Access funding enabled and organized by Projekt DEAL. （TUM）

光：科学与应用（英文版）

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ISSN：2095-5545

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