摘要
Abstract
Objective To analyze the intervention effects of different pre-hospital care modes in severe acute organophosphorus pesticide poisoning (SAOPP) patients. 70 patients with SAOPP who were admitted to the Central Hospital of Kaifeng City from January 2021 to June 2022 were selected as the research subjects. They were grouped according to the time period. Patients who were transferred and received pre-hospital emergency treatment at the same time from January 2021 to September 2021 were set as the reference group. Patients who received pre-hospital emergency treatment first and then in-hospital treatment from October 2021 to June 2022 were set as the research group, each with 35 cases. In the reference group, pre-hospital emergency treatment was carried out at the same time as the transfer, while in the research group, pre-hospital emergency treatment was carried out first, followed by further in-hospital treatment. A comparative analysis was conducted on the success rate and recovery rate of patients in each group Clinical related indicators (ChE recovery time, symptom disappearance time, Atropine treatment time, hospital stay, dosage of Iodine Pralidoxime, dosage of Atropine), complications (intermediate syndrome, Respiratory failure, delayed nerve injury, heart damage, Atropine poisoning), cortisol, adrenocortical hormone levels, and quality of life. Results The success rate and cure rate of rescue in the study group accounted for 91.43% and 96.88%, respectively, which were higher than those in the reference group (71.43% and 68.00%). After comparison, there was a signi?cant di?erence (P<0.05); The recovery time of ChE, the time of symptom disappearance, the time of hospitalization, and the time of Atropine transformation in the study group were shorter than those in the reference group. At the same time, the dosage of Pralidoxime iodide and Atropine was less, which was signi?cantly di?erent from the reference group (P<0.05); In addition, the incidence of complications is low, and the levels of cortisol and adrenocorticotropic hormone increase after treatment, which is signi?cantly di?erent from the reference group (P<0.05); After treatment, the quality of life in the study group was scored higher, and there was a signi?cant di?erence compared to the reference group (P<0.05). Conclusion The mode of ?rst aid followed by transportation in SAOPP is more conducive to improving treatment e?ectiveness, reducing complications, reducing mortality, and further improving quality of life.关键词
有机磷农药中毒/重度/阿托品/胆碱酯酶/院前急救Key words
organophosphorus pesticide poisoning/severe/atropine/cholinesterase/pre-hospital care分类
医药卫生