临床与病理杂志2023，Vol.43Issue(9)：1649-1655,7.DOI:10.11817/j.issn.2095-6959.2023.230040
MRI多序列在多发性硬化颈髓病变检测效能中的比较
Comparison of multi-sequence MRI in cervical cord lesions for multiple sclerosis
摘要
Abstract
Objective:To compare the differences in detecting cervical spinal cord lesions in patients with multiple sclerosis(MS)using the 3D-phase sensitive inversion recovery(3D-PSIR),short time inversion recovery(STIR),and T2 weighted imaging(T2WI). Methods:A total of 34 MS patients who underwent cervical spinal cord MRI examinations in the Second Affiliated to Air Force Medical University from February 2022 to September 2022 were included in this study.All patients underwent magetic resonance imaging(MRI)with T2WI,STIR and 3D-PSIR.The effectiveness,quantity,localization,and acquisition time of detecting cervical spinal cord lesions were observed and compared among different sequences,and the lesion-to-cord contrast ratio differences were analyzed between the 3D-PSIR and the STIR. Results:There was a statistically significant difference in the number of lesions detected among the 3D-PSIR,T2WI and STIR(F=24.76,P<0.001).Pairwise comparisons showed that there were statistically significant differences in lesion detection between any 2 sequences(all P<0.01).The lesion detection rate of the 3D-PSIR was approximately 37.9%,which was higher than that of conventional sequences.The 3D-PSIR demonstrated advantages in all cervical spinal cord positions,and the axial localization accuracy had statistically significantly different from T2WI(P<0.05).The 3D-PSIR had a higher lesion-to-spinal cord image contrast compare with the STIR(1.68 vs 0.45,t=10.47,P<0.001).Replacing the STIR and T2WI sequences with the 3D-PSIR sequence could reduce the scan time by 4.37 minutes and improve the efficiency by 59.5%. Conclusion:The 3D-PSIR sequence is of great significance for detecting MS spinal cord lesions and can provide a valuable MRI imaging method for visualizing other cervical spinal cord lesions.关键词
多发性硬化/磁共振成像/颈髓/3D相位敏感反转恢复序列Key words
multiple sclerosis/magnetic resonance imaging/cervical cord/3D-phase sensitive inversion recovery引用本文复制引用
魏熠鑫,袁梦晖,白芡蓉,李云波,郭智瑞,张春梅,张微,郭俊,李宏增,王玮..MRI多序列在多发性硬化颈髓病变检测效能中的比较[J].临床与病理杂志,2023,43(9):1649-1655,7.基金项目
国家自然科学基金(82171339) （82171339）
陕西省重点研发计划项目(2022ZDLSF02-04).This work was supported by the National Natural Science Foundation(82171339)and the Key Research and Development Plan Program of Shaanxi Province(2022ZDLSF02-04),China. （2022ZDLSF02-04）
