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医用99Mo工业化生产技术研发

张建栋 陈真 陈雅宏

同位素2023,Vol.36Issue(6):620-632,13.
同位素2023,Vol.36Issue(6):620-632,13.DOI:10.7538/tws.2022.youxian.055

医用99Mo工业化生产技术研发

Current Developments in the Industry Production Process of 99Mo for Medical Use

张建栋 1陈真 1陈雅宏1

作者信息

  • 1. 成都欣科医药有限公司,成都 610200
  • 折叠

摘要

Abstract

The aging of global research reactors has led to a serious shortage of target irradiation capacity for industrial production of 99Mo,as well as restrictions on the civil-ian use of high enriched uranium under the Nuclear Non Proliferation Treaty.This has forced the exploration of new production processes for 99Mo and the conversion of exist-ing high enriched uranium targets to low enriched uranium targets.In the process of exploring new technologies and target conversion,it has caused a global shortage of medical 99Mo supply,endangering people's health.The United States,Canada,and Europe are intensifying their exploration of new process technologies for the commer-cialization and stable supply of medical 99Mo,such as exploring irradiation targets with as accelerator particle beams,subcritical devices,small reactors,molten salt stacks,and solution stacks,using new materials and processes to prepare targets,and applying supercritical,ionic liquids,and new chromatographic columns to the preparation of 99Mo.The production of low enriched uranium targets is gradually replacing high enriched uranium targets.The photonuclear reaction process has matured,and proces-ses such as low-power research reactors,subcritical devices,and particle beams can meet the needs of some local radioactive drugs and nuclear medicine.The active research on accelerator production technology is the development direction of future medical 99Mo production.

关键词

99Mo生产技术/99Mo分离/99Mo纯化/高比活度/99Mo/99m Tc发生器

Key words

99Mo production technology/99Mo separation/99Mo purification/high specific activity/99Mo/99m Tc generator

分类

能源科技

引用本文复制引用

张建栋,陈真,陈雅宏..医用99Mo工业化生产技术研发[J].同位素,2023,36(6):620-632,13.

同位素

OACSTPCD

1000-7512

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