畜牧与兽医2023，Vol.55Issue(12)：13-20,8.
泽泻粉对高能低蛋白日粮诱导的蛋鸡肝脏脂沉积的缓解作用
Alisma powder alleviates high energy and low protein diet-induced hepatic lipid deposition in laying hens
摘要
Abstract
The aim of the trial was to explore the effect of Alisma powder in alleviating high energy and low protein diet-induced hepatic lipid deposition in laying hens.Seventy-two 260-day-old Hy-Line Variety Brown laying hens were obtained and randomly divided into three groups,namely,the control group(CON,treated with 10.9 MJ/kg metabolizable energy,16.9％crude protein),the high-energy and low-protein diet group(HF,with 13.0 MJ/kg metabolizable energy,12.1％crude protein),and the high-energy low-protein diet supplemented with Alisma powder group(HFA,with 13.0 MJ/kg metabolizable energy,12.1％crude protein,supplemented with 72 mg/kg Alisma pow-der).The hens were housed in cages and subjected to restricted feeding with 110 g/d/head.The room temperature of the chicken house was about 24 ℃,the light regime was 16L:8D,and the test period was 12 weeks.The results showed that the egg production rate,egg weight,egg quality index,plasma alanine aminotransferase activity,total cholesterol and triglyceride concentration in the HF group were not signifi-cantly different from those in the control group(P＞0.05),whereas the content of triglycerides in their liver was significantly(P＜0.05)higher than that of the control group;and adding Alisma powder to the diet significantly alleviated the hepatic lipid deposition of the laying hens,and at the same time significantly(P＜0.05)reversed the up-regulation of fatty acid synthase,acetyl-CoA carboxylase 1 and stearoyl-CoA desaturase-1 mRNA of the hepatic lipid synthetic genes.Simultaneously,the upregulation of hepatic glucocorticoid receptor(GR)mRNA and protein was also significantly alleviated in the hens.These results suggested that Alisma alleviated hepatic lipid metabolic disorder induced by high-energy and low-protein diets by regulating de novo lipogenesis in laying hens.GR might be involved in the signaling pathway of the function of alisma.关键词
泽泻粉/脂代谢/脂质从头合成/糖皮质激素受体Key words
Alisma powder/lipid metabolism/lipid de novo synthesis/GR分类
农业科技引用本文复制引用
李炎林,蒋文夺,冯跃,贾逸敏,赵茹茜..泽泻粉对高能低蛋白日粮诱导的蛋鸡肝脏脂沉积的缓解作用[J].畜牧与兽医,2023,55(12):13-20,8.基金项目
国家自然科学基金(32272962,31972638) （32272962,31972638）
国家重点研发计划(2022YFD1300401) （2022YFD1300401）
