局解手术学杂志2023，Vol.32Issue(12)：1054-1058,5.DOI:10.11659/jjssx.02E023029
不同术前营养评分系统在肝细胞癌切除术预后评估中的意义
Significance of different preoperative nutritional scoring systems in prognosis evaluation of radical resection of hepatocellular carcinoma
摘要
Abstract
Objective To evaluate the relationship between preoperative prognostic nutritional index(PNI),controlling nutritional status(CONUT)and Naples prognostic score(NPS)and the clinicopathological characteristics and prognosis of patients with radical resection of hepatocellular carcinoma.Methods The clinicopathological data of 122 patients with hepatocellular carcinoma who underwent radical resection in the first affiliated hospital of university of science and technology of China from January 2016 to December 2019 were retrospec-tively analyzed,and the relationship between preoperative PNI,CONUT and NPS and the clinicopathological characteristics and prognosis was analyzed.The survival curve was drawn by Kaplan-Meier method.Cox proportional-hazards regression model was used to analyze the influencing factors of the overall survival of hepatocellular carcinoma patients.The area under the receiver operating characteristic(ROC)curve(AUC)was used to compare the predictive value of each scoring system.Results Preoperative PNI was related to the tumor differentiation,microvascular invasion(MVI),cirrhosis and preoperative hemoglobin level(P<0.05).The preoperative CONUT was related to the tumor differentiation,cirrhosis and preoperative hemoglobin level(P<0.05).The preoperative NPS was related to the cirrhosis and preoperative hemoglobin level(P<0.05).The low PNI group,high CONUT group and high NPS group had longer postoperative hospital stay and higher postoperative complications rate compared with the high PNI group,low CONUT group and low NPS group,respectively,and the differences were statistically significant(P<0.05).Cox proportional-hazards regression model showed that preoperative PNI,CONUT and NPS were associated with the prognosis of patients with hepatocellular carcinoma(P<0.05);However,only preoperative NPS was the independent risk factor for prognosis of patients with hepatocellular carcinoma(P<0.05).The ROC curve results showed that the AUC of NPS was higher than those of PNI and CONUT.Conclusion preoperative PNI,CONUT and NPS are all related to the prognosis of hepatocellular carcinoma patients undergoing radical resection,and the predictive value of preoperative NPS is higher than preoperative PNI and CONUT.关键词
肝细胞癌/预后营养指数/控制营养状态/那不勒斯预后评分/预后Key words
hepatocellular carcinoma/prognostic nutritional index/controlling nutritional status/Naples prognostic score/prognosis分类
医药卫生引用本文复制引用
陆明,胡孔旺,涂从银..不同术前营养评分系统在肝细胞癌切除术预后评估中的意义[J].局解手术学杂志,2023,32(12):1054-1058,5.基金项目
安徽省科技厅重点研究与开发项目(202004j07020036) （202004j07020036）
