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复发性舌鳞状细胞癌复发时间及预后相关影响因素研究

侯承素 殷玉兰 张于涵 王磊 张野 张士剑

中国实用口腔科杂志2023,Vol.16Issue(6):676-681,693,7.
中国实用口腔科杂志2023,Vol.16Issue(6):676-681,693,7.DOI:10.19538/j.kq.2023.06.007

复发性舌鳞状细胞癌复发时间及预后相关影响因素研究

Study on recurrence time and prognostic factors of recurrent tongue squamous cell carcinoma

侯承素 1殷玉兰 1张于涵 2王磊 2张野 1张士剑3

作者信息

  • 1. 上海第九人民医院集团奉城医院·上海市奉贤区奉城医院口腔颌面-头颈肿瘤科,上海 201411
  • 2. 国家口腔临床研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科,上海 200011
  • 3. 国家口腔临床研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科,上海 200011||海南省口腔临床医学中心(筹),张志愿院士工作站,上海第九人民医院集团(海南)儋州医联体,海南西部中心医院口腔颌面外科,海南儋州 571700
  • 折叠

摘要

Abstract

Objective The risk factors related to recurrence time and prognosis of recurrent tongue squamous cell carci-noma(rTSCC)were analyzed.Methods A total of 177 rTSCC patients admitted to the Ninth People's Hospital Affiliat-ed to Shanghai Jiao Tong University School of Medicine and the Department of Oral and Maxillofacial-Head and Neck Oncology of Fengcheng Hospital,Fengxian District,Shanghai,from January 2012 to June 2017 were collected.Clinico-pathological data and survival information of the patients were collected.The factors related to recurrence time and prog-nosis of rTSCC patients were analyzed.Results Recur-rent lesions may involve the anatomical structures of the contralateral tongue,floor of the mouth,hyoid bone,man-dible,epiglottis,parapharynx,and tongue base.The recur-rence time of rTSCC patients was significantly correlated with gender and smoking history,and the differences were statistically significant(P<0.05).Comparative analysis of the 3-year survival rate and 5-year survival rate of pa-tients showed that the T stage,surgical margin,N stage,clinical stage and histopathological grade of recurrent tu-mor were significantly correlated with the prognosis of re-current patients,and the above factors and the time of tu-mor recurrence all affected the overall survival of pa-tients,the difference being with statistical significance(P<0.05).Conclusion Clinicians should focus on improving the analysis of staging,grading and other data of rTSCC patients,and advise patients to develop good living habits,in or-der to prolong the survival time of patients.

关键词

舌鳞状细胞癌/复发/预后

Key words

tongue squamous cell carcinoma/recurrence/prognosis

分类

医药卫生

引用本文复制引用

侯承素,殷玉兰,张于涵,王磊,张野,张士剑..复发性舌鳞状细胞癌复发时间及预后相关影响因素研究[J].中国实用口腔科杂志,2023,16(6):676-681,693,7.

基金项目

上海交通大学"交大之星"计划医工交叉研究基金(YG2022QN061) (YG2022QN061)

海南省自然科学基金(823MS158) (823MS158)

奉贤区科委社会类科技发展基金(20201502 ()

20231201) ()

中国实用口腔科杂志

OACSCDCSTPCD

1674-1595

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