中国药理学通报2023，Vol.39Issue(12)：2225-2230,6.DOI:10.12360/CPB202207051
神经血管偶联与中枢神经系统疾病
Neurovascular coupling and central nervous system diseases
摘要
Abstract
Neurovascular coupling is the function of regulating blood flow of the central nervous system at the level of neurovas-cular units.The central nervous system diseases related to neu-rovascular coupling mainly include cerebrovascular diseases such as chronic cerebral ischemia and neurodegenerative diseases such as Alzheimer's disease,Parkinson's disease and Lewy body dementia.The main mechanism of neurovascular coupling dys-function leading to the above diseases is cerebrovascular dys-function or loss,which leads to serious damage to neuronal ische-mia and affects its function.Therefore,this paper reviews the re-search status of neurovascular coupling and its related central nervous system diseases,in order to guide the follow-up re-search.The purpose of this paper is to provide a basis for the prevention,relief and treatment of central nervous system disea-ses related to neurovascular coupling through the mechanism of neurovascular coupling.关键词
神经血管偶联/神经血管单元/调控机制/研究方法/中枢神经系统疾病/活性物质Key words
neurovascular coupling/neurovascular units/regu-latory mechanism/research methods/central nervous system diseases/active substance分类
医药卫生引用本文复制引用
杨鞠祥,张钊,楚世峰,贺文彬,李刚,陈乃宏..神经血管偶联与中枢神经系统疾病[J].中国药理学通报,2023,39(12):2225-2230,6.基金项目
国家自然科学基金资助项目(No U21A20410) （No U21A20410）
山西省重点研发计划(No 201803D421006,201903D421018) （No 201803D421006,201903D421018）
中医脑病学山西省重点实验室开放课题基金资助 （）
