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胆汁酸影响乙肝疫苗免疫应答的研究进展

朱俐燕 胡丹丹

中山大学学报(医学科学版)2023,Vol.44Issue(6):910-914,5.
中山大学学报(医学科学版)2023,Vol.44Issue(6):910-914,5.

胆汁酸影响乙肝疫苗免疫应答的研究进展

Research Progress on the Influence of Bile Acids on the Immune Response of Hepatitis B Vaccine

朱俐燕 1胡丹丹1

作者信息

  • 1. 广州医科大学附属广州市妇女儿童医疗中心,广东 广州 510623
  • 折叠

摘要

Abstract

Hepatitis B vaccine(HepB)vaccination is the safest and most effective means of preventing hepatitis B vi-rus(HBV)infection.HepB non-response is influenced by multiple factors,and solving the problem of poor immune re-sponse after HepB vaccination is of great significance for controlling HBV infection.Bile acids play an important role in hu-man immune regulation,and whether bile acids have an effect on the HepB immune response has not been definitively studied.This article reviews the correlation between bile acids and HepB immune response,and provides a reference for further clarifying the pathogenesis and immunoprevention of bile acids in vaccine immunity.

关键词

胆汁酸/乙型肝炎疫苗/免疫应答/T淋巴细胞/干扰素/白细胞介素

Key words

bile acids/hepatitis B vaccine/immune response/T-lymphocyte/interferon/terleukin

分类

医药卫生

引用本文复制引用

朱俐燕,胡丹丹..胆汁酸影响乙肝疫苗免疫应答的研究进展[J].中山大学学报(医学科学版),2023,44(6):910-914,5.

基金项目

广州市重点研发计划项目(202206010060) (202206010060)

广州市科技计划项目(202201020648) (202201020648)

中山大学学报(医学科学版)

OA北大核心CSCDCSTPCD

1672-3554

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