中山大学学报（医学科学版）2023，Vol.44Issue(6)：915-924,10.
分子靶向药物治疗肝细胞癌的研究进展
Advances in Molecular Targeted Drugs for Hepatocellular Carcinoma
摘要
Abstract
Being the most common solid malignant tumor in the digestive system and the third leading cause of cancer-related death worldwide,hepatocellular carcinoma(HCC)is characterized by insidious onset,early recurrence/metastasis and poor prognosis.With the advantages of targeted precision,high specificity,minimal drug resistance,remarkable thera-peutic efficacy and fewer side effects,molecular targeted drugs have become the hotspot and focus of tumor therapy research in recent years.As more is learned about the mechanism and clinical efficacy,some molecular targeted drugs have been rec-ommended by HCC treatment guidelines.This paper reviewed the mechanism of HCC targeted therapy,molecular targeted drugs,relevant therapeutic protocols and outcomes so as to provide reference and evidence for subsequent research.关键词
肝细胞癌/分子靶向药物/指南/联合治疗/索拉非尼Key words
hepatocellular carcinoma(HCC)/molecular targeted drugs/guidelines/combination therapy/sorafenib分类
医药卫生引用本文复制引用
王耀民,李亚玲..分子靶向药物治疗肝细胞癌的研究进展[J].中山大学学报（医学科学版）,2023,44(6):915-924,10.基金项目
四川省科技厅资助项目(2022YFS0625) （2022YFS0625）
