中山大学学报（医学科学版）2023，Vol.44Issue(6)：925-930,6.
乌帕替尼治疗克罗恩病的研究进展
Research Progress of Upadacitinib in the Treatment of Crohn's Disease
樊慧丰 1周秀彦2
作者信息
- 1. 山西医科大学第二临床医学院,山西 太原 030000
- 2. 山西医科大学第二医院消化科,山西 太原 030000
- 折叠
摘要
Abstract
Crohn's Disease(CD)is a destructive,relapsing and remitting chronic inflammatory bowel disease that usually progresses to irreversible intestinal structural and functional changes,such as intestinal lumen stenosis,fistula for-mation and perianal lesions,severely affecting the quality of life of patients.This review summarized the research progress on the mechanism,clinical application and safety of upadacitinib in the treatment of CD.Upadacitinib can increase the clinical remission and endoscopic response rates in patients with CD,improve the long-term outcome of CD patients and provide a new idea for the treatment of CD patients by using biological agents.关键词
乌帕替尼/克罗恩病/发病机制/疗效/药物安全性Key words
upadacitinib/Crohn's Disease/pathogenesis/curative effect/drug safety分类
医药卫生引用本文复制引用
樊慧丰,周秀彦..乌帕替尼治疗克罗恩病的研究进展[J].中山大学学报（医学科学版）,2023,44(6):925-930,6.
