赣南医学院学报2023,Vol.43Issue(10):1037-1041,5.DOI:10.3969/j.issn.1001-5779.2023.10.008
肿瘤相关巨噬细胞在甲状腺癌中的研究进展
Research progress of tumor-associated macrophages in thyroid cancer
摘要
Abstract
Thyroid cancer is the most common malignancy among head and neck cancers.Tumor associated macrophages are the most important component of the tumor microenvironment with high plasticity.When the microenvironment changes,they can be polarized into lassic activated macrophages(M1)and bypass activated macrophages(M2).M2/M1 has a great correlation with the poor prognosis of thyroid cancer.Tumor associated macrophages play an important role in the occurrence,development,invasion and metastasis of thyroid cancer.This article reviews the origin and plasticity of tumor associated macrophages,the mechanism of action in thyroid cancer and the regulatory pathways in thyroid cancer,intending to provide new ideas for the treatment.关键词
肿瘤相关巨噬细胞/甲状腺癌/肿瘤微环境Key words
Tumor associated macrophages/Thyroid cancer/Tumor microenvironment分类
医药卫生引用本文复制引用
郜小妮,戴孟桥,李佳根,刘梅玉,谢洋,刘家锋,应勇,曾祥泰..肿瘤相关巨噬细胞在甲状腺癌中的研究进展[J].赣南医学院学报,2023,43(10):1037-1041,5.基金项目
赣州市科技局科技计划项目(202101124805) (202101124805)