海南医学院学报2023，Vol.29Issue(23)：1836-1840,5.DOI:10.13210/j.cnki.jhmu.20230217.002
口腔黏膜下纤维性变癌变的分子机制研究进展
Advances in molecular mechanisms of oral submucosal fibrogenic carcinogenesis
摘要
Abstract
Oral submucous fibrosis(OSF)is a chronic,progressive and insidious oral mucosal disease.Its development is highly associated with areca chewing and eventually evolves into oral squamous cell carcinoma(OSCC),which is currently recog-nized as a precancerous state by the International Agency for Research on Cancer(IARC).Due to the extremely complex carcino-genesis process of OSF,the carcinogenesis mechanism is not clear,and most scholars believe that the disease is the result of multi-ple factors.Therefore,this paper mainly summarized the latest research on the molecular mechanism of OSF cancerization,aiming at understanding the law of OSF cancerization and providing theoretical reference for early detection,diagnosis and treatment of OSF cancerization.关键词
口腔黏膜下纤维性变/癌变/机制Key words
Oral submucous fibrosis/Carcinogenesis/Mechanism分类
医药卫生引用本文复制引用
李冰霞,温琦涛,王涛,孙冠宇,符骁,苏守达..口腔黏膜下纤维性变癌变的分子机制研究进展[J].海南医学院学报,2023,29(23):1836-1840,5.基金项目
This study was supported by National Natural Science Foundation of China(81960199) （81960199）
Major Science and Technology Plan and Key R&D Plan Project of Hainan Province(ZDYF2021SHFZ114) （ZDYF2021SHFZ114）
Hainan Provincial Department of Health Project(22A200001) 国家自然科学基金(81960199) （22A200001）
海南省重大科技计划、省重点研发计划项目(ZDYF2021SHFZ114) （ZDYF2021SHFZ114）
海南省卫生厅项目(22A200001) （22A200001）
