海洋科学2023，Vol.47Issue(9)：103-118,16.DOI:10.11759/hykx20230208001
海洋环境中氟喹诺酮类抗生素(FQs)分析的样品前处理与检测技术
Sample pretreatment and determination of fluoroquinolone antibiotics in marine environments
摘要
Abstract
Fluoroquinolones(FQs)from a class of widely used synthetic antibiotics and exist in various environ-mental media,such as water and sediments.FQs are gradually enriched in aquatic organisms,posing a negative effect on human health and the sustainable development of the global ecosystem.Determining the FQ residues in the environment is the foundation for understanding their environmental biogeochemical behavior and potential ecological risks.This article systematically summarizes the results related to the features,as well as the sample pretreatment and determination of the FQ residues in seawater,sediments,and biological samples obtained in recent years.Accordingly,the development trend of sample pretreatment and determination methods for FQ analysis in marine environments is discussed.The physical and chemical properties,along with the complexity of sample compositions,must be considered during the sample pretreatment and determination of FQs.Sediment and biologi-cal samples should be prepared to remove more water,select the appropriate extraction solvent,and employ ultra-sonic-assisted extraction,considering the matrix effect and pH.Solid-phase extraction(SPE),QuEChERS extrac-tion,and magnetic solid-phase extraction are common methods for the separation and enrichment of FQs.The se-lection and optimization of the eluting solution are key factors for improving sample recovery.The determination of FQs is mostly carried out through liquid chromatography-tandem mass spectrometry or liquid chromatography combined with a fluorescence detector,wherein selecting the chromatographic column,adding an ion-pairing agent,and adjusting pH are the key factors.In future research,more attention should be paid to the development of online automatic SPE technology and new extraction adsorbents.关键词
氟喹诺酮类抗生素(FQs)/样品前处理/分离富集/海洋环境Key words
Fluoroquinolones antibiotics(FQs)/sample preparation/separation and enrichment/marine environment分类
资源环境引用本文复制引用
温丽联,宋金明,李学刚,马骏,戴佳佳,袁华茂,段丽琴,王启栋..海洋环境中氟喹诺酮类抗生素(FQs)分析的样品前处理与检测技术[J].海洋科学,2023,47(9):103-118,16.基金项目
中国科学院A类先导专项项目(XDA23050501) （XDA23050501）
中国科学院特别研究助理支持项目 the Strategic Priority Research Program of the Chinese Academy of Sciences,No.XDA23050501 （）
Special Research Assistant Support Program of the Chinese Academy of Sciences （）
