实用临床医药杂志2023，Vol.27Issue(22)：77-80,85,5.DOI:10.7619/jcmp.20232280
急性前循环闭塞患者血管内治疗后无效再通的多因素分析
Multivariate analysis of futile recanalization after intravascular therapy in patients with acute anterior circulation occlusion
摘要
Abstract
Objective To explore the incidence and risk factors of futile recanalization after in-travascular therapy in patients with acute anterior circulation occlusion.Methods Clinical materials of 176 patients with acute anterior circulation occlusion in the registration system of the Stroke Center of the Affiliated Hospital of Nantong University from August 2015 to December 2021 were retrospec-tively analyzed.All the patients received intravascular therapy to successfully achieve angiographic re-canalization[grade of modified thrombolysis in cerebral infarction(mTICI)≥2b],and were divided into futile recanalization group[score of modified Rankin Scale(mRS)was 3 to 6 points]and effec-tive recanalization group(mRS score was 0 to 2 points)based on functional independence at 90 days after surgery.Logistic regression analysis was used to identify predictors of futile recanalization after intravascular treatment.Results In the 176 patients,93 patients had futile recanalization,and 83 patients had effective recanalization.There were significant differences in age,gender,atrial fibrilla-tion,score of the National Institute of Health Stroke Scale(NIHSS)on hospital admission,ischemic time,bridging treatment and hemorrhagic transformation between the futile recanalization group and the effective recanalization group(P＜0.05).Multivariate Logistic regression analysis showed that high NIHSS score on hospital admission(OR=0.815,95％CI,0.760 to 0.874,P＜0.001)and ischemic time(OR=1.232,95％CI,1.020 to 1.488,P=0.030)were the independent predictors of futile recanalization.Conclusion The incidence of futile recanalization after intravascular treat-ment is relatively high in patients with acute anterior circulation occlusion,while age,gender,atrial fibrillation,high NIHSS score on hospital admission,ischemic time,bridging treatment and hemor-rhagic transformation are the risk factors for futile recanalization after intravascular treatment in AIS patients,and high NIHSS score on hospital admission and ischemic time are the independent predic-tive factors for futile recanalization after intravascular treatment in AIS patients.关键词
急性前循环闭塞/血管内治疗/无效再通/改良脑梗死溶栓分级/美国国立卫生研究院卒中量表Key words
acute anterior circulation occlusion/intravascular treatment/futile recanaliza-tion/modified thrombolysis in cerebral infarction/the National Institute of Health Stroke Scale分类
医药卫生引用本文复制引用
吉云鹏,刘泳欣,何爽,张云峰..急性前循环闭塞患者血管内治疗后无效再通的多因素分析[J].实用临床医药杂志,2023,27(22):77-80,85,5.基金项目
国家自然科学基金面上项目(81870941) （81870941）
江苏省南通市公众健康面上项目(MS22022058) （MS22022058）
