实用临床医药杂志2023，Vol.27Issue(22)：81-85,5.DOI:10.7619/jcmp.20230109
绘画联合药物干预对焦虑障碍患者心理状态、依从性和生活质量的影响
Effects of painting combined with drug intervention on mental states,compliance and quality of life in patients with anxiety disorder
摘要
Abstract
Objective To analyze the effects of painting and medication intervention on psycho-logical state,compliance and quality of life in patients with generalized anxiety disorder(GAD).Methods A total of 70 patients with GAD from May 2020 to September 2022 were included as study subjects,among whom 35 patients receiving single drug intervention were included in single group,and 35 patients receiving painting combined drug intervention were included in combined group.The psychological state scores and intervention compliance of the subjects in the two groups were ana-lyzed,the life quality scores and serum factor expression levels of the subjects in the two groups were compared before and after intervention,and the changes in sleep quality of the two groups were ob-served before and after intervention.Results After intervention,the scores of Hamilton Anxiety Rat-ing Scale(HAMA),Hamilton Depression Rating Scale(HAMD)in the two groups were decreased compared with those before intervention,but their scores in the combined group were lower,and the differences were statistically significant(P＜0.05).The total compliance rate of the combined group was higher than that of the single group(P＜0.05).After intervention,the 36-item Shot-form Health Status Survey(SF-36)scores of the two groups were improved compared with that before intervention,and the SF-36 score of the combined group was higher,the difference was statistically significant(P＜0.05).After intervention,the expression levels of brain derived neurotrophic factor(BDNF)and malondialdehyde(MDA)in the combined group were lower than those in the single group,and the expression level of superoxide dismutase(SOD)was higher than those in the single group(P＜0.05).After intervention,the sleep quality of the two groups was improved compared with that be-fore intervention,but the improvement degree of the combined group was higher(P＜0.05).Conclusion Painting combined with drug intervention can effectively improve the adverse psycho-logical state of GAD patients,improve their intervention compliance,and further improve their qual-ity of life and sleep quality.关键词
绘画干预/焦虑障碍/心理状态/依从性/生活质量Key words
painting intervention/anxiety disorder/mental state/compliance/quality of life分类
医药卫生引用本文复制引用
刘贵香,安金媚,侯继崇,宋暖,赵月霞..绘画联合药物干预对焦虑障碍患者心理状态、依从性和生活质量的影响[J].实用临床医药杂志,2023,27(22):81-85,5.基金项目
河北省医学科学研究课题计划项目(20221498) （20221498）
