精准医学杂志2024，Vol.39Issue(1)：67-70,4.DOI:10.13362/j.jpmed.202401017
劈离式肝移植术后成功妊娠分娩1例并文献复习
Successful pregnancy and delivery after split liver transplantation:A case report and literature re-view
赵柳 1徐琳 2刘虹 1郭源 1李志强 1蔡金贞 1臧运金 1饶伟1
作者信息
- 1. 青岛大学附属医院器官移植中心,肝脏病中心,山东 青岛 266100||青岛大学移植医学研究所
- 2. 青岛大学附属医院产科
- 折叠
摘要
Abstract
Objective To investigate the experience in the clinical management of pregnancy and delivery after split liver transplantation(SLT).Methods Related clinical data were collected from a patient who became pregnant and delivered success-fully after SLT in the Organ Transplantation Center of our hospital,and a literature review was also performed.Results The patient underwent allogeneic orthotopic SLT due to decompensated liver cirrhosis after autoimmune hepatitis and developed mild acute rejection after surgery,which was improved after the adjustment of immunosuppressive drugs.The patient became pregnant spontaneously at 2 years after surgery,and due to the medication history of mycophenolate sodium enteric-coated tablets,she de-cided to terminate pregnancy and withdraw from this drug.The patient became pregnant again at 3 years after surgery and expe-rienced fluctuations in graft function,and a series of treatments were given,such as adjustment of the dose of anti-rejection drugs,liver-protecting symptomatic treatment,and tocolytic therapy for threatened preterm labor.Finally under the guidance of liver transplantation,obstetrics,and neonatology,the patient gave birth to a healthy girl by cesarean section at 35 weeks of gestation.Conclusion Although SLT recipients may experience the situations such as fluctuations in graft function and preterm birth,they can achieve a satisfactory prognosis under multidisciplinary collaboration,scientific medication guidance,and close follow-up moni-toring.关键词
肝移植/预后/妊娠/免疫抑制剂/移植物排斥/肝功能不全Key words
Liver transplantation/Prognosis/Pregnancy/Immunosuppressive agents/Graft rejection/Hepatic insuffi-ciency分类
医药卫生引用本文复制引用
赵柳,徐琳,刘虹,郭源,李志强,蔡金贞,臧运金,饶伟..劈离式肝移植术后成功妊娠分娩1例并文献复习[J].精准医学杂志,2024,39(1):67-70,4.
