精准医学杂志2024，Vol.39Issue(1)：71-73,77,4.DOI:10.13362/j.jpmed.202401018
多米诺肝移植临床效果分析(附2例报告)
Clinical efficacy of domino liver transplantation:An analysis of two cases
张慧 1王建红 1王淑贤 1冯帅 1刘金泉 1徐祥美 1戴德淑 1孙爽 1许传屾1
作者信息
- 1. 青岛大学附属医院器官移植中心,山东 青岛 266003
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of domino liver transplantation(DLT)and to provide a refe-rence for expanding the sources of donor livers.Methods The clinical data of two cases who underwent DLT at our hospital in 2021 were collected,and a literature review was performed.Results Donor 1 was a healthy subject,recipient 1(DLT donor)was a patient with ornithine transcarbamylase deficiency,and recipient 2(DLT recipient)was a patient with Cirgler-Najiar syn-drome.Donor 2 was a brain-dead donor as per the internationally standardized definitions,recipient 3(DLT donor)was a patient with familial hypercholesterolemia,and recipient 4(DLT recipient)was a patient with malignant liver tumor.After transplanta-tion,all patients experienced recovery of their liver function in 1 week,and were discharged from the hospital after 2 to 4 weeks of hospitalization.Recipient 2 developed thrombosis in the left portal vein on day 4 after operation;after emergent thrombolysis and anticoagulant therapy,the blood flow of the portal vein was effectively improved,and no serious outcomes were identified;the bili-rubin level of the patient returned to normal at 1 week after operation.Recipient 4 developed hyperlipidemia after operation and was treated with atorvastatin and ezetimibe for lipid regulation;the patient was followed up till now with no additional complications found.Conclusion DLT can effectively expand the sources of donor livers.关键词
肝移植/移植受体/活体供者/治疗结果/病例报告Key words
Liver transplantation/Transplant recipients/Living donors/Treatment outcome/Case reports分类
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张慧,王建红,王淑贤,冯帅,刘金泉,徐祥美,戴德淑,孙爽,许传屾..多米诺肝移植临床效果分析(附2例报告)[J].精准医学杂志,2024,39(1):71-73,77,4.
