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核酸农药纳米递送系统研究进展

何承帅 张辉 吴顺凡 高云昊 高聪芬

农药学学报2023,Vol.25Issue(6):1179-1197,19.
农药学学报2023,Vol.25Issue(6):1179-1197,19.DOI:10.16801/j.issn.1008-7303.2023.0083

核酸农药纳米递送系统研究进展

Advance of nucleic acid pesticide delivery systems mediated by nanomaterial

何承帅 1张辉 1吴顺凡 1高云昊 1高聪芬1

作者信息

  • 1. 南京农业大学 绿色农药创制与应用技术国家地方联合工程研究中心,植物保护学院,南京 210095
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摘要

Abstract

With the development of science and technology,more attention has been focused on human health and environmental safety.Green pesticides will be the development trend of pesticides in the future.Compared to traditional chemical pesticides,specific targeting,environmental safety,and easy development were among the advantages of nucleic acid pesticides.However,there are great challenges in delivering the effector molecules of nucleic acid pesticides(dsRNA/siRNA)to the tissues or cells of target organisms.In recent years,nucleic acid pesticide delivery systems based on various types of nanomaterials have been developed to address this issue.The approaches and challenges of applying nucleic acid pesticides,as well as the advantages,mechanisms,and novel nanomaterials used in nanomaterial-mediated nucleic acid pesticide delivery systems,are reviewed in this paper.The prospects of nanomaterial-mediated delivery systems for nucleic acid pesticides are also prospected.

关键词

核酸农药/dsRNA/siRNA/纳米材料/递送系统

Key words

nucleic acid pesticides/dsRNA/siRNA/nanomaterials/delivery systems

分类

生物科学

引用本文复制引用

何承帅,张辉,吴顺凡,高云昊,高聪芬..核酸农药纳米递送系统研究进展[J].农药学学报,2023,25(6):1179-1197,19.

基金项目

国家重点研发计划项目"重要病虫害抗药性机制与治理技术研发"(2022YFD1400900). Supported by National Key Research and Development Program of China(No.2022YFD1400900). (2022YFD1400900)

农药学学报

OA北大核心CSCDCSTPCD

1008-7303

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